Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SCARB1 | Q8WTV0 | 1/20 | 0.32 |
| ▸ | LSS | P48449 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10420328 | 1.00 | KCNH2 (0.40) | KCNH2HRH3LTA4HCYP1A2CYP19A1 | |
| SCHEMBL9862966 | 0.85 | NPC1 (0.35) | MEN1KMT2ASCARB1MAPK1KDM4E | |
| SCHEMBL9862967 | 0.85 | NPC1 (0.35) | MEN1KMT2ASCARB1MAPK1KDM4E | |
| SCHEMBL9705902 | 0.84 | NR1I2 (0.30) | MEN1KMT2A | |
| SCHEMBL9705896 | 0.84 | NR1I2 (0.30) | MEN1KMT2A | |
| SCHEMBL9666126 | 0.83 | KCNH2 (0.51) | KCNH2HRH3LTA4HCYP1A2CYP19A1 | |
| SCHEMBL9668318 | 0.82 | KCNH2 (0.50) | KCNH2HRH3LTA4HCYP1A2CYP19A1 | |
| SCHEMBL9705718 | 0.82 | KCNH2 (0.50) | KCNH2HRH3LTA4HCYP1A2CYP19A1 | |
| SCHEMBL9666409 | 0.82 | KCNH2 (0.50) | KCNH2HRH3LTA4HCYP1A2CYP19A1 | |
| Disoxaril SCHEMBL147146 | 0.82 | KCNH2 (0.50) | KCNH2HRH3LTA4HCYP1A2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5002960-A | Viricides for combating picornaviruses | STERLING DRUG, INC. (US) | 1991-03-26 | — | — | US | disclosed |
| US-4939267-A | Viricides | STERLING DRUG INC. (US) | 1990-07-03 | — | — | US | disclosed |
| US-4843087-A | OXAZOLINYL COMPOUNDS; RHINOVIRUSES AND PICORNAVIRUSES | STERLING DRUG INC. (US) | 1989-06-27 | — | — | US | disclosed |