Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | TK1 | P04183 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | HBB | P68871 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | TK2 | O00142 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9706120 | 0.91 | LMNA (0.45) | LMNASMN1; SMN2TK1MAPTTSHR | |
| SCHEMBL9706090 | 0.89 | LMNA (0.49) | LMNASMN1; SMN2TK1MAPTTSHR | |
| SCHEMBL9706133 | 0.87 | TK1 (0.48) | LMNATK1ADRA1A | |
| SCHEMBL9311378 | 0.84 | LMNA (0.62) | LMNASMN1; SMN2TK1MAPTTSHR | |
| SCHEMBL9706119 | 0.81 | TK1 (0.61) | TK1TSHRPMP22TK2 | |
| SCHEMBL16300453 | 0.80 | LMNA (0.52) | LMNASMN1; SMN2TK1MAPTTSHR | |
| SCHEMBL600100 | 0.79 | LMNA (0.56) | LMNASMN1; SMN2TK1MAPTTSHR | |
| SCHEMBL599660 | 0.79 | LMNA (0.53) | LMNASMN1; SMN2TK1MAPTTSHR | |
| SCHEMBL10172064 | 0.79 | LMNA (0.53) | LMNASMN1; SMN2TK1MAPTTSHR | |
| SCHEMBL10515491 | 0.79 | LMNA (0.56) | LMNASMN1; SMN2TK1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0481320-A1 | Novel cyclobutane derivatives | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1992-04-22 | — | — | EP | disclosed |