Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 8/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | PNP | P00491 | 1/20 | 0.39 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 7/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 7/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 7/20 | 0.36 |
| ▸ | CCNA1 | P78396 | 7/20 | 0.36 |
| ▸ | MGMT | P16455 | 3/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.35 |
| ▸ | PI4KA | P42356 | 2/20 | 0.35 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.35 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.35 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16146634 | 0.82 | CDK2 (0.45) | PDPK1GDACDK2MAP3K5CDK1 | |
| SCHEMBL27870406 | 0.80 | PDPK1 (0.61) | PDPK1GDACDK2DPP4MAP3K5 | |
| SCHEMBL29375265 | 0.76 | PDPK1 (0.66) | PDPK1GDACDK2DPP4PNP | |
| SCHEMBL8851 | 0.76 | PDPK1 (0.66) | PDPK1GDACDK2DPP4PNP | |
| SCHEMBL2526552 | 0.75 | PDPK1 (0.44) | PDPK1GDACDK2DPP4PNP | |
| SCHEMBL3313639 | 0.72 | PI4KA (0.57) | PDPK1CDK2MAP3K5ALDH1A1PI4KA | |
| SCHEMBL16146695 | 0.72 | PDPK1 (0.41) | PDPK1GDACDK2DPP4PNP | |
| SCHEMBL11212991 | 0.72 | PDPK1 (0.41) | PDPK1GDACDK2DPP4PNP | |
| SCHEMBL356178 | 0.72 | DPP4 (0.61) | PDPK1GDACDK2DPP4PNP | |
| SCHEMBL2350025 | 0.72 | GDA (0.41) | PDPK1GDACDK2DPP4PNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992011276-A1 | NOVEL SYNTHESIS OF 2'-'UP' FLUORINATED 2''-DEOXY-ARABINOFURANOSYLPURINES | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1992-07-09 | — | — | WO | disclosed |