Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.51 |
| ▸ | HPGDS | O60760 | 3/20 | 0.48 |
| ▸ | ALPI | P09923 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | XIAP | P98170 | 1/20 | 0.47 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | FCER2 | P06734 | 3/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | MME | P08473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5597677 | 1.00 | EPHX1 (0.51) | EPHX1HPGDSALPIPKMPTGS1 | |
| SCHEMBL17078155 | 0.86 | CYP3A4 (0.50) | EPHX1HPGDSALPIPKMPTGS1 | |
| SCHEMBL9706212 | 0.86 | EPHX1 (0.51) | EPHX1HPGDSALPIPKMPTGS1 | |
| SCHEMBL8843830 | 0.86 | EPHX1 (0.51) | EPHX1HPGDSALPIPKMPTGS1 | |
| SCHEMBL23925862 | 0.85 | MME (0.56) | CYP1A2MME | |
| SCHEMBL1921156 | 0.85 | MME (0.56) | CYP1A2MME | |
| SCHEMBL1921155 | 0.85 | MME (0.56) | CYP1A2MME | |
| SCHEMBL11254313 | 0.84 | EPHX1 (0.50) | EPHX1HPGDSALPIPKMPTGS1 | |
| SCHEMBL989835 | 0.84 | SIGMAR1 (0.53) | EPHX1HPGDSALPIPKMPTGS1 | |
| SCHEMBL4672507 | 0.84 | SIGMAR1 (0.53) | EPHX1HPGDSALPIPKMPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1441724-B8 | METHODS OF INCREASING ENDOGENOUS TESTOSTERONE LEVELS | SERONO LAB (CH) | 2007-10-17 | — | — | EP | claimed |
| JP-2005504093-A | — | — | 2005-02-10 | — | — | JP | claimed |
| EP-1441724-A1 | METHODS OF INCREASING ENDOGENOUS TESTOSTERONE LEVELS | Applied Research Systems ARS Holding S.A. (AN) | 2004-08-04 | — | — | EP | claimed |
| WO-2003026649-A1 | METHODS OF INCREASING ENDOGENOUS TESTOSTERONE LEVELS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2003-04-03 | — | — | WO | claimed |
| EP-1282418-A2 | USE OF PYRAZOLE DERIVATIVES FOR TREATING INFERTILITY | Serono Reproductive Biology Institute, Inc. (US) | 2003-02-12 | — | — | EP | claimed |
| WO-2001087287-A2 | USE OF PYRAZOLE DERIVATIVES FOR TREATING INFERTILITY | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2001-11-22 | — | — | WO | claimed |
| EP-1441724-B8 | METHODS OF INCREASING ENDOGENOUS TESTOSTERONE LEVELS | SERONO LAB (CH) | 2007-10-17 | — | — | EP | disclosed |
| EP-1441724-A1 | METHODS OF INCREASING ENDOGENOUS TESTOSTERONE LEVELS | Applied Research Systems ARS Holding S.A. (AN) | 2004-08-04 | — | — | EP | disclosed |
| WO-2003026649-A1 | METHODS OF INCREASING ENDOGENOUS TESTOSTERONE LEVELS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2003-04-03 | — | — | WO | disclosed |
| EP-1282418-A2 | USE OF PYRAZOLE DERIVATIVES FOR TREATING INFERTILITY | Serono Reproductive Biology Institute, Inc. (US) | 2003-02-12 | — | — | EP | disclosed |
| WO-2001087287-A2 | USE OF PYRAZOLE DERIVATIVES FOR TREATING INFERTILITY | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2001-11-22 | — | — | WO | disclosed |