Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 6/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 2/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.37 |
| ▸ | PGR | P06401 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9706248 | 1.00 | SHBG (0.57) | SHBGMAPK1POLBARNR3C1 | |
| SCHEMBL9705862 | 0.97 | SHBG (0.56) | SHBGMAPK1POLBARNR3C1 | |
| SCHEMBL9705866 | 0.97 | SHBG (0.56) | SHBGMAPK1POLBARNR3C1 | |
| SCHEMBL10883085 | 0.93 | SHBG (0.57) | SHBGMAPK1POLBARNR3C1 | |
| SCHEMBL10883090 | 0.93 | SHBG (0.57) | SHBGMAPK1POLBARNR3C1 | |
| SCHEMBL9706264 | 0.91 | SHBG (0.57) | SHBGMAPK1POLBARNR3C1 | |
| SCHEMBL9706258 | 0.91 | SHBG (0.57) | SHBGMAPK1POLBARNR3C1 | |
| SCHEMBL10408625 | 0.90 | SHBG (0.56) | SHBGMAPK1POLBARNR3C1 | |
| SCHEMBL10408627 | 0.90 | SHBG (0.56) | SHBGMAPK1POLBARNR3C1 | |
| SCHEMBL10408955 | 0.89 | SHBG (0.55) | SHBGMAPK1POLBARNR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0218647-B1 | SKIN TREATMENT AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-06-17 | — | — | EP | disclosed |
| US-4859659-A | ACNE TREATMENT | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-08-22 | — | — | US | disclosed |
| EP-0071153-B1 | ANDROSTANE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCHERING AKTIENGESELLSCHAFT (DE) | 1986-09-10 | — | — | EP | disclosed |
| US-4587235-A | Novel androstane derivatives, process for their production, and pharmaceutical preparations containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1986-05-06 | — | — | US | disclosed |
| US-4457925-A | Androstane derivatives, process for their production, and pharmaceutical preparations containing them | SCHERING, AKTIENGESELLSCHAFT (DE) | 1984-07-03 | — | — | US | disclosed |