Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 6/20 | 0.57 |
| ▸ | STS | P08842 | 7/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B3 | P37058 | 3/20 | 0.40 |
| ▸ | AR | P10275 | 2/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9706264 | 1.00 | SHBG (0.57) | SHBGSTSPOLBMAPK1HSD17B3 | |
| SCHEMBL10408625 | 0.97 | SHBG (0.56) | SHBGSTSPOLBMAPK1HSD17B3 | |
| SCHEMBL10408627 | 0.97 | SHBG (0.56) | SHBGSTSPOLBMAPK1HSD17B3 | |
| SCHEMBL10408953 | 0.96 | SHBG (0.55) | SHBGSTSPOLBMAPK1HSD17B3 | |
| SCHEMBL10408955 | 0.96 | SHBG (0.55) | SHBGSTSPOLBMAPK1HSD17B3 | |
| Rosterolone SCHEMBL141283 | 0.93 | SHBG (0.57) | SHBGSTSPOLBMAPK1HSD17B3 | |
| Rosterolone SCHEMBL8724124 | 0.93 | SHBG (0.57) | SHBGSTSPOLBMAPK1HSD17B3 | |
| Rosterolone SCHEMBL7094611 | 0.93 | SHBG (0.57) | SHBGSTSPOLBMAPK1HSD17B3 | |
| SCHEMBL9706248 | 0.91 | SHBG (0.57) | SHBGSTSPOLBMAPK1AR | |
| SCHEMBL9706243 | 0.91 | SHBG (0.57) | SHBGSTSPOLBMAPK1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4892867-A | Antiandrogenic 17-alpha-alkyl steroids | SCHERING AKTIENGESELLSCHAFT (DE) | 1990-01-09 | — | — | US | claimed |
| EP-0027961-B1 | 17-ALPHA-SUBSTITUTED STEROIDS, PREPARATIONS CONTAINING THEM AND PROCESS FOR THEIR PRODUCTION | SCHERING AKTIENGESELLSCHAFT (DE) | 1983-01-12 | — | — | EP | claimed |
| EP-0027961-A1 | 17-alpha-substituted steroids, preparations containing them and process for their production | SCHERING AKTIENGESELLSCHAFT (DE) | 1981-05-06 | — | — | EP | claimed |
| EP-0218647-B1 | SKIN TREATMENT AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-06-17 | — | — | EP | disclosed |
| US-4892867-A | Antiandrogenic 17-alpha-alkyl steroids | SCHERING AKTIENGESELLSCHAFT (DE) | 1990-01-09 | — | — | US | disclosed |
| US-4859659-A | ACNE TREATMENT | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-08-22 | — | — | US | disclosed |
| US-4558041-A | ACNE, DEPILATORIES; BALDNESS | SCHERING AKTIENGESELLSCHAFT (DE) | 1985-12-10 | — | — | US | disclosed |
| US-4456600-A | Antiandrogenic 17α-alkyl steroids | SCHERING, AKTIENGESELLSCHAFT (A.G.) (DE) | 1984-06-26 | — | — | US | disclosed |
| US-4344941-A | Antiandrogenic 17α-substituted steroids | SCHERING AKTIENGESELLSCHAFT (A.G.) (DE) | 1982-08-17 | — | — | US | disclosed |
| EP-0027961-A1 | 17-alpha-substituted steroids, preparations containing them and process for their production | SCHERING AKTIENGESELLSCHAFT (DE) | 1981-05-06 | — | — | EP | disclosed |