Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.44 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.44 |
| ▸ | ALB | P02768 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.44 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.44 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.43 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.41 |
| ▸ | NT5E | P21589 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9706072 | 0.91 | LMNA (0.42) | LMNAPDE3ACACNA1FALBMAPT | |
| SCHEMBL9706206 | 0.89 | LMNA (0.46) | LMNAPDE3ACACNA1FALBMAPT | |
| SCHEMBL9311419 | 0.84 | LMNA (0.54) | LMNAPDE3ACACNA1FALBMAPT | |
| SCHEMBL8541693 | 0.79 | LMNA (0.50) | LMNAPDE3ACACNA1FALBMAPT | |
| SCHEMBL10468438 | 0.79 | LMNA (0.55) | LMNAPDE3ACACNA1FALBMAPT | |
| SCHEMBL10421043 | 0.79 | LMNA (0.50) | LMNAPDE3ACACNA1FALBMAPT | |
| SCHEMBL9471029 | 0.79 | LMNA (0.55) | LMNAPDE3ACACNA1FALBMAPT | |
| SCHEMBL8797148 | 0.79 | LMNA (0.50) | LMNAPDE3ACACNA1FALBMAPT | |
| SCHEMBL9471195 | 0.79 | LMNA (0.50) | LMNAPDE3ACACNA1FALBMAPT | |
| SCHEMBL8541689 | 0.79 | LMNA (0.50) | LMNAPDE3ACACNA1FALBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0481320-A1 | Novel cyclobutane derivatives | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1992-04-22 | — | — | EP | disclosed |