Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.79 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.79 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.57 |
| ▸ | NPC1 | O15118 | 5/20 | 0.57 |
| ▸ | RAB9A | P51151 | 5/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | CASP3 | P42574 | 2/20 | 0.57 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.57 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | TP53 | P04637 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benoxaprofen SCHEMBL29364205 | 0.88 | MAOA (1.00) | MAOAADRA1ASMN1; SMN2NPC1RAB9A | |
| Benoxaprofen SCHEMBL24413 | 0.88 | MAOA (1.00) | MAOAADRA1ASMN1; SMN2NPC1RAB9A | |
| Flunoxaprofen SCHEMBL29612240 | 0.88 | MAOA (0.78) | MAOAADRA1ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL5476419 | 0.88 | MAOA (0.78) | MAOAADRA1ASMN1; SMN2NPC1RAB9A | |
| Flunoxaprofen SCHEMBL25196 | 0.88 | MAOA (0.78) | MAOAADRA1ASMN1; SMN2NPC1RAB9A | |
| Benoxaprofen SCHEMBL24414 | 0.88 | MAOA (1.00) | MAOAADRA1ASMN1; SMN2NPC1RAB9A | |
| Flunoxaprofen SCHEMBL25195 | 0.88 | MAOA (0.78) | MAOAADRA1ASMN1; SMN2NPC1RAB9A | |
| Benoxaprofen SCHEMBL11246423 | 0.87 | MAOA (0.98) | MAOAADRA1ASMN1; SMN2NPC1RAB9A | |
| Benoxaprofen SCHEMBL28038058 | 0.87 | MAOA (0.98) | MAOAADRA1ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL11695483 | 0.85 | MAOA (0.65) | MAOAADRA1ASMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0485173-A2 | Esters and amides of substituted fused ring phenyl acetic acids | FGN, INC. (US) | 1992-05-13 | — | — | EP | disclosed |