Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | KDM4A | O75164 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10184936 | 0.81 | TSHR (0.58) | TSHRALDH1A1LMNAKDM4EKDM4A | |
| SCHEMBL9437154 | 0.80 | POLB (0.45) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL9706431 | 0.79 | L3MBTL1 (0.45) | TSHRALDH1A1LMNAKDM4ETP53 | |
| SCHEMBL7568997 | 0.78 | TSHR (0.66) | TSHRALDH1A1LMNAKDM4ETP53 | |
| SCHEMBL27571636 | 0.76 | ALDH1A1 (0.75) | TSHRALDH1A1LMNAKDM4ETP53 | |
| SCHEMBL9808837 | 0.76 | POLB (0.46) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL6868825 | 0.75 | TSHR (0.57) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL6400485 | 0.75 | ALDH1A1 (0.60) | TSHRALDH1A1LMNAKDM4ETP53 | |
| SCHEMBL6405721 | 0.75 | ALDH1A1 (0.60) | TSHRALDH1A1LMNAKDM4ETP53 | |
| SCHEMBL6407768 | 0.75 | ALDH1A1 (0.60) | TSHRALDH1A1LMNAKDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0500210-A2 | Liquid crystal compounds and compositions | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 1992-08-26 | — | — | EP | disclosed |