Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.52 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29104167 | 0.97 | NAAA (0.48) | NAAAHRH1ALDH1A1TSHR | |
| SCHEMBL2411378 | 0.81 | — | — | |
| SCHEMBL14305750 | 0.78 | NAAA (0.50) | NAAAALDH1A1L3MBTL1 | |
| SCHEMBL9741621 | 0.78 | NAAA (0.50) | NAAAHRH1 | |
| SCHEMBL29263650 | 0.78 | NAAA (0.50) | NAAAHRH1 | |
| SCHEMBL7524061 | 0.78 | NAAA (0.50) | NAAAALDH1A1L3MBTL1 | |
| SCHEMBL15225261 | 0.78 | NAAA (0.50) | NAAAALDH1A1L3MBTL1 | |
| SCHEMBL9819021 | 0.78 | NAAA (0.50) | NAAAALDH1A1L3MBTL1 | |
| SCHEMBL483412 | 0.78 | NAAA (0.50) | NAAAALDH1A1L3MBTL1 | |
| SCHEMBL9319665 | 0.78 | NAAA (0.50) | NAAAHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0198325-B1 | SUBSTITUTED ANILINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1992-07-15 | — | — | EP | disclosed |
| US-4891429-A | CHEMICAL INTERMEDIATES | HOFFMANN-LA ROCHE INC. (US) | 1990-01-02 | — | — | US | disclosed |
| US-4696930-A | CARDIOVASCULAR DISORDERS, ANTICOAGULANTS | HOFFMANN-LA ROCHE INC. (US) | 1987-09-29 | — | — | US | disclosed |
| EP-0198325-A2 | Substituted aniline derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1986-10-22 | — | — | EP | disclosed |