Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPOX | P50336 | 7/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
| ▸ | GUSB | P08236 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10647226 | 0.89 | KDM4E (0.43) | PPOXSMN1; SMN2HPGDLMNAMAPT | |
| SCHEMBL10649863 | 0.87 | SMN1; SMN2 (0.36) | PPOXSMN1; SMN2HPGDLMNAMAPT | |
| SCHEMBL10649870 | 0.87 | SMN1; SMN2 (0.35) | SMN1; SMN2HPGDLMNAMAPTKDM4E | |
| SCHEMBL10645249 | 0.86 | SMN1; SMN2 (0.34) | SMN1; SMN2HPGDLMNAMAPTKDM4E | |
| SCHEMBL9706637 | 0.86 | SMN1; SMN2 (0.34) | SMN1; SMN2HPGDLMNAMAPTKDM4E | |
| SCHEMBL9706633 | 0.86 | HPGD (0.34) | PPOXSMN1; SMN2HPGDLMNAMAPT | |
| SCHEMBL9706651 | 0.85 | PPOX (0.34) | PPOXSMN1; SMN2HPGDLMNAMAPT | |
| SCHEMBL9423141 | 0.84 | TSHR (0.36) | PPOXSMN1; SMN2HPGDMAPTALDH1A1 | |
| SCHEMBL9706661 | 0.83 | GABRA1 (0.33) | — | |
| SCHEMBL9706675 | 0.83 | PPOX (0.36) | PPOXSMN1; SMN2HPGDLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0195346-B1 | 3-ARYL URACILES AND THEIR USE AS HERBICIDES | CIBA-GEIGY AG (CH) | 1992-06-24 | — | — | EP | claimed |
| US-4760163-A | 3-(5-carboxy-4-substituted-phenyl)-(thio)uracil-esters and salts | HOFFMANN-LAROCHE INC. (US) | 1988-07-26 | — | — | US | disclosed |
| US-4746352-A | HERBICIDES | HOFFMANN-LA ROCHE INC. (US) | 1988-05-24 | — | — | US | disclosed |