Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 9/20 | 0.36 |
| ▸ | MYC | P01106 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | CASP6 | P55212 | 1/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9706621 | 0.91 | NOTUM (0.36) | NOTUMMYCTDP1NR4A1CTSB | |
| SCHEMBL9706710 | 0.88 | NOTUM (0.34) | NOTUMMYCTDP1NR4A1CTSB | |
| SCHEMBL9706662 | 0.87 | NOTUM (0.40) | NOTUMMYCTDP1NR4A1CTSB | |
| SCHEMBL9706512 | 0.86 | NOTUM (0.41) | NOTUMMYCTDP1NR4A1CTSB | |
| SCHEMBL9706659 | 0.86 | NOTUM (0.39) | NOTUMMYCTDP1NR4A1CTSB | |
| SCHEMBL10646945 | 0.85 | LMNA (0.34) | ALDH1A1POLBHPGDSMN1; SMN2 | |
| SCHEMBL9706639 | 0.84 | NOTUM (0.38) | NOTUMMYCTDP1NR4A1CTSB | |
| SCHEMBL9706670 | 0.84 | NOTUM (0.38) | NOTUMMYCTDP1NR4A1CTSB | |
| SCHEMBL9706666 | 0.81 | NOTUM (0.42) | NOTUMMYCTDP1NR4A1CTSB | |
| SCHEMBL24151268 | 0.80 | NOTUM (0.38) | NOTUMMYCTDP1NR4A1CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0195346-B1 | 3-ARYL URACILES AND THEIR USE AS HERBICIDES | CIBA-GEIGY AG (CH) | 1992-06-24 | — | — | EP | disclosed |
| US-4760163-A | 3-(5-carboxy-4-substituted-phenyl)-(thio)uracil-esters and salts | HOFFMANN-LAROCHE INC. (US) | 1988-07-26 | — | — | US | disclosed |
| US-4746352-A | HERBICIDES | HOFFMANN-LA ROCHE INC. (US) | 1988-05-24 | — | — | US | disclosed |