SCHEMBL9706710

SCHEMBL9706710

COCc1c(C)n(C)c(=O)n(-c2cc(C(=O)O)c(Cl)cc2F)c1=O

nearest known ligand 0.34

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 8/20 0.34
TDP1 Q9NUW8 2/20 0.31
ALDH1A1 P00352 2/20 0.31
HPGD P15428 1/20 0.31
MAPK1 P28482 1/20 0.31
MYC P01106 1/20 0.31
NR4A1 P22736 1/20 0.31
CTSB P07858 1/20 0.31
KDM4E B2RXH2 1/20 0.31
MAPT P10636 1/20 0.31
GRM4 Q14833 1/20 0.30
PTGER4 P35408 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9706626 0.88 NOTUM (0.36) NOTUMTDP1ALDH1A1HPGDMYC
SCHEMBL9706621 0.88 NOTUM (0.36) NOTUMTDP1ALDH1A1HPGDMYC
SCHEMBL9706668 0.87 LMNA (0.33) HPGDMAPT
SCHEMBL9706512 0.85 NOTUM (0.41) NOTUMTDP1ALDH1A1HPGDMYC
SCHEMBL9706662 0.84 NOTUM (0.40) NOTUMTDP1ALDH1A1HPGDMYC
SCHEMBL9706659 0.83 NOTUM (0.39) NOTUMTDP1ALDH1A1HPGDMYC
SCHEMBL9706639 0.81 NOTUM (0.38) NOTUMTDP1ALDH1A1HPGDMYC
SCHEMBL9706670 0.81 NOTUM (0.38) NOTUMTDP1ALDH1A1HPGDMYC
SCHEMBL9706666 0.81 NOTUM (0.42) NOTUMTDP1MYCNR4A1CTSB
SCHEMBL10650900 0.79 LMNA (0.33) HPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0195346-B1 3-ARYL URACILES AND THEIR USE AS HERBICIDES CIBA-GEIGY AG (CH) 1992-06-24 EP claimed