Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SOD1 | P00441 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | FLT1 | P17948 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16483016 | 0.88 | MEN1 (0.50) | MAPTPLAUFFAR4MEN1KMT2A | |
| SCHEMBL16930011 | 0.86 | MAPT (0.46) | MAPTPLAUFFAR4MEN1KMT2A | |
| SCHEMBL17125227 | 0.83 | MAPT (0.43) | MAPTPLAUFFAR4MEN1KMT2A | |
| SCHEMBL18860591 | 0.83 | MAPT (0.43) | MAPTPLAUFFAR4MEN1KMT2A | |
| SCHEMBL18860620 | 0.83 | MAPT (0.43) | MAPTPLAUFFAR4MEN1KMT2A | |
| SCHEMBL15720769 | 0.82 | MAPT (0.42) | MAPTPLAUFFAR4MEN1KMT2A | |
| SCHEMBL12128097 | 0.82 | KCNH2 (0.43) | MAPTPLAUFFAR4MEN1KMT2A | |
| SCHEMBL18860542 | 0.82 | EGFR (0.47) | MAPTPLAUFFAR4MEN1KMT2A | |
| SCHEMBL5175776 | 0.80 | PLA2G2A (0.51) | MAPTPLAUFFAR4MEN1KMT2A | |
| SCHEMBL366495 | 0.79 | HTT (0.57) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5174893-A | Process for dehalogenation of contaminated waste materials | CHEMICAL WASTE MANAGEMENT, INC. (US) | 1992-12-29 | — | — | US | disclosed |
| EP-0491452-A1 | Process for dehalogenation | CHEMICAL WASTE MANAGEMENT, INC. (US) | 1992-06-24 | — | — | EP | disclosed |
| US-5093011-A | Detoxification of halogenated aromatics; pollution control | CHEMICAL WASTE MANAGEMENT, INC. (US) | 1992-03-03 | — | — | US | disclosed |
| EP-0456457-A1 | Process for dehalogenation | CHEMICAL WASTE MANAGEMENT, INC. (US) | 1991-11-13 | — | — | EP | disclosed |
| US-5043054-A | Process for dehalogenation of contaminated waste materials | CHEMICAL WASTE MANAGEMENT, INC. (US) | 1991-08-27 | — | — | US | disclosed |