SCHEMBL9706665

SCHEMBL9706665

C=CCSCc1c[nH]c(=O)[nH]c1=O

nearest known ligand 0.44

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DPYD Q12882 1/20 0.44
CYP3A4 P08684 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4344338 0.84 DPYD (0.45) DPYD
SCHEMBL4356407 0.81 ATAD2 (0.44)
SCHEMBL175877 0.77 DPYD (0.52) DPYD
SCHEMBL4346481 0.76 DPYD (0.45) DPYD
SCHEMBL30464746 0.74 CYP3A4 (0.49) DPYDCYP3A4
SCHEMBL30464745 0.74 CYP3A4 (0.49) DPYDCYP3A4
SCHEMBL30582772 0.72 DPYD (0.47) DPYDCYP3A4
SCHEMBL536006 0.70
SCHEMBL4353311 0.69 DPYD (0.50) DPYD
SCHEMBL5800398 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0195346-B1 3-ARYL URACILES AND THEIR USE AS HERBICIDES CIBA-GEIGY AG (CH) 1992-06-24 EP disclosed
EP-0195346-A2 3-Aryl uraciles and their use as herbicides CIBA-GEIGY AG (CH) 1986-09-24 EP disclosed