SCHEMBL175877

SCHEMBL175877

C=CCc1c[nH]c(=O)[nH]c1=O

nearest known ligand 0.52

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
DPYD Q12882 2/20 0.52
GAA P10253 2/20 0.48
ATAD2 Q6PL18 1/20 0.42
ALDH1A1 P00352 1/20 0.42
LMNA P02545 1/20 0.42
MAPT P10636 1/20 0.42
CYP19A1 P11511 1/20 0.42
TSHR P16473 1/20 0.42
THPO P40225 1/20 0.42
MTOR P42345 1/20 0.42
HTT P42858 1/20 0.42
HBB P68871 1/20 0.42
PMP22 Q01453 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29822911 0.82 DPYD (0.44) DPYDGAAATAD2ALDH1A1LMNA
SCHEMBL30464745 0.81 CYP3A4 (0.49) DPYD
SCHEMBL30464746 0.81 CYP3A4 (0.49) DPYD
SCHEMBL15554789 0.81 GAA (0.35) DPYDGAAALDH1A1
SCHEMBL11735379 0.81 KMT2A (0.46) DPYDGAAALDH1A1
SCHEMBL439999 0.77 DPYD (0.40) DPYDGAA
SCHEMBL148954 0.77 DPYD (0.40) DPYDGAA
SCHEMBL28838402 0.77 DPYD (0.40) DPYDGAA
SCHEMBL9706665 0.77 DPYD (0.44) DPYD
SCHEMBL4353311 0.76 DPYD (0.50) DPYDGAAATAD2ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1827 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250320496-A1 MODULATION OF ABCB11 GENE TRANSCRIPTION USING ANTISENSE OLIGONUCLEOTIDES TARGETING REGULATORY RNAS CAMP4 THERAPEUTICS CORPORATION 2025-10-16 US claimed
EP-4627084-A1 MODULATION OF SYNGAP1 GENE TRANSCRIPTION USING ANTISENSE OLIGONUCLEOTIDES TARGETING REGULATORY RNAS Camp4 Therapeutics Corporation (US) 2025-10-08 EP claimed
US-20250290072-A1 MODULATION OF SYNGAP1 GENE TRANSCRIPTION USING ANTISENSE OLIGONUCLEOTIDES TARGETING REGULATORY RNAS CAMP4 THERAPEUTICS CORPORATION 2025-09-18 US claimed
US-20250250575-A1 MODULATION OF GENE TRANSCRIPTION USING ANTISENSE OLIGONUCLEOTIDES TARGETING REGULATORY RNAS CAMP4 THERAPEUTICS CORPORATION 2025-08-07 US claimed
US-20250243488-A1 METHODS OF MODULATING PROGRANULIN EXPRESSION USING ANTISENSE OLIGONUCLEOTIDES TARGETING REGULATORY RNAS CAMP4 THERAPEUTICS CORPORATION 2025-07-31 US claimed
WO-2024119145-A9 MODULATION OF SYNGAP1 GENE TRANSCRIPTION USING ANTISENSE OLIGONUCLEOTIDES TARGETING REGULATORY RNAS CAMP4 THERAPEUTICS CORPORATION (US) 2025-06-19 WO claimed
EP-4536831-A2 METHODS OF MODULATING PROGRANULIN EXPRESSION USING ANTISENSE OLIGONUCLEOTIDES TARGETING REGULATORY RNAS Camp4 Therapeutics Corporation (US) 2025-04-16 EP claimed
CN-119731320-A Methods of modulating expression of granulin precursors using antisense oligonucleotides targeted to regulatory RNAs 4阵营疗法公司 2025-03-28 CN claimed
US-20240360451-A1 MODULATION OF GENE TRANSCRIPTION USING ANTISENSE OLIGONUCLEOTIDES TARGETING REGULATORY RNAS CAMP4 THERAPEUTICS CORPORATION 2024-10-31 US claimed
EP-4453211-A1 MODULATION OF GENE TRANSCRIPTION USING ANTISENSE OLIGONUCLEOTIDES TARGETING REGULATORY RNAS Camp4 Therapeutics Corporation (US) 2024-10-30 EP claimed
US-20050215513-A1 Use of an antiviral compound linked to one or more phosphonate groups in hepatitis C treatment; improved bioavailability, side effect reduction; antiviral compound is a 2-(2-isopropylaminothiazol-4-yl)-4-(tricyclic fused ring)-7-methoxy-quinoline compound GILEAD SCIENCES, INC. 2005-09-29 US claimed
EP-0898575-B1 A COMBINATORIAL PROTECTING GROUP STRATEGY FOR MULTIFUNCTIONAL MOLECULES KOESTER HUBERT DR (US) 2004-12-29 EP claimed
WO-2004096286-A2 ANTIVIRAL PHOSPHONATE ANALOGS GILEAD SCIENCES, INC. (US) 2004-11-11 WO claimed
WO-2004096824-A2 NUCLEOSIDE DERIVATIVE, MODIFIED OLIGONUCLEOTIDE, METHOD FOR THEIR SYNTHESIS AND APPLICATIONS THEREOF CENTRUM MIKROBIOLOGII I WIRUSOLOGII POLSKIEJ AKADEMII NAUK (PL) 2004-11-11 WO claimed
WO-2004096233-A2 NUCLEOSIDE PHOSPHONATE CONJUGATES GILEAD SCIENCES, INC. (US) 2004-11-11 WO claimed
US-20030194741-A1 COMBINATORIAL PROTECTING GROUP STRATEGY FOR MULTIFUNCTIONAL MOLECULES CAPROTEC BIOANALYTICS GMBH (DE) 2003-10-16 US claimed
US-20030054410-A1 Combinatorial protecting group strategy for multifunctional molecules CAPROTEC BIOANALYTICS GMBH (DE) 2003-03-20 US claimed
US-5891684-A RIBOZYMES RIBOZYME PHARMACEUTICALS, INC. (US) 1999-04-06 US claimed
EP-0898575-A2 A COMBINATORIAL PROTECTING GROUP STRATEGY FOR MULTIFUNCTIONAL MOLECULES KÖSTER, Hubert (US) 1999-03-03 EP claimed
WO-1997041139-A2 A COMBINATORIAL PROTECTING GROUP STRATEGY FOR MULTIFUNCTIONAL MOLECULES KOESTER HUBERT (US) 1997-11-06 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030194741-A1 COMBINATORIAL PROTECTING GROUP STRATEGY FOR MULTIFUNCTIONAL MOLECULES ADAR, RNMT, ATIC DPYD 519/4885GAA 3190/4885ATAD2 2080/4885
US-20240360451-A1 MODULATION OF GENE TRANSCRIPTION USING ANTISENSE OLIGONUCLEOTIDES TARGETING REGULATORY RNAS OTC, ODC1, POU2F1 DPYD 977/4885GAA 423/4885ATAD2 1523/4885
US-20050215513-A1 Use of an antiviral compound linked to one or more phosphonate groups in hepatitis C treatment; improved bioavailability, side effect reduction; antiviral compound is a 2-(2-isopropylaminothiazol-4-yl)-4-(tricyclic fused ring)-7-methoxy-quinoline compound EIF2AK2, PNP, NUDT1 DPYD 522/4885GAA 595/4885ATAD2 3174/4885
US-20250320496-A1 MODULATION OF ABCB11 GENE TRANSCRIPTION USING ANTISENSE OLIGONUCLEOTIDES TARGETING REGULATORY RNAS ABCB11, SLC10A1, SREBF1 DPYD 2772/4885GAA 2677/4885ATAD2 1641/4885
US-20250250575-A1 MODULATION OF GENE TRANSCRIPTION USING ANTISENSE OLIGONUCLEOTIDES TARGETING REGULATORY RNAS CPS1, CTPS1, CTPS2 DPYD 1073/4885GAA 529/4885ATAD2 1746/4885
US-20030054410-A1 Combinatorial protecting group strategy for multifunctional molecules ADAR, RNMT, RRM1 DPYD 362/4885GAA 2513/4885ATAD2 1865/4885
US-20250243488-A1 METHODS OF MODULATING PROGRANULIN EXPRESSION USING ANTISENSE OLIGONUCLEOTIDES TARGETING REGULATORY RNAS GRN, SNRPE, UPF1 DPYD 2827/4885GAA 230/4885ATAD2 1815/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.