Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CASP6 | P55212 | 2/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9706593 | 0.98 | TDP1 (0.48) | TDP1CTSBALDH1A1L3MBTL1POLB | |
| SCHEMBL10647208 | 0.84 | PARP1 (0.47) | ALDH1A1L3MBTL1MEN1KMT2AHPGD | |
| SCHEMBL9706647 | 0.84 | SLC6A2 (0.37) | TDP1CTSBALDH1A1L3MBTL1POLB | |
| SCHEMBL9706611 | 0.82 | KDM4E (0.46) | ALDH1A1L3MBTL1MEN1KMT2AHPGD | |
| SCHEMBL9706536 | 0.79 | HPGD (0.38) | TDP1ALDH1A1L3MBTL1POLBMEN1 | |
| SCHEMBL9706673 | 0.77 | HPGD (0.40) | TDP1ALDH1A1L3MBTL1POLBMEN1 | |
| SCHEMBL9706652 | 0.75 | TDP1 (0.50) | TDP1CTSBALDH1A1L3MBTL1POLB | |
| SCHEMBL10649882 | 0.74 | TDP1 (0.49) | TDP1CTSBALDH1A1L3MBTL1POLB | |
| SCHEMBL9706570 | 0.73 | TDP1 (0.50) | TDP1CTSBALDH1A1L3MBTL1POLB | |
| SCHEMBL10647253 | 0.71 | SLC6A2 (0.38) | TDP1CTSBALDH1A1L3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0195346-B1 | 3-ARYL URACILES AND THEIR USE AS HERBICIDES | CIBA-GEIGY AG (CH) | 1992-06-24 | — | — | EP | claimed |