Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9675915 | 0.88 | MAPT (0.50) | CYP19A1ALDH1A1MAPTGAATDP1 | |
| SCHEMBL9706750 | 0.85 | NAPRT (0.42) | ALDH1A1MAPTGAASMN1; SMN2NPC1 | |
| SCHEMBL9674962 | 0.85 | CYP19A1 (0.52) | CYP19A1ALDH1A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL9672860 | 0.81 | ADRA1A (0.62) | ALDH1A1MAPTGAATDP1SMN1; SMN2 | |
| SCHEMBL2488639 | 0.80 | MAPT (0.70) | CYP19A1ALDH1A1MAPTGAATDP1 | |
| SCHEMBL9706743 | 0.79 | PTPN1 (0.46) | ALDH1A1MAPTGAASMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL7020139 | 0.79 | MAPT (0.68) | CYP19A1ALDH1A1MAPTGAATDP1 | |
| SCHEMBL9621031 | 0.78 | ADRA1A (0.55) | ALDH1A1MAPTGAASMN1; SMN2MEN1 | |
| SCHEMBL25698340 | 0.78 | CYP19A1 (0.49) | CYP19A1ALDH1A1MAPTGAATDP1 | |
| SCHEMBL8531170 | 0.77 | ADRA1A (0.46) | ALDH1A1MAPTGAATDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5158950-A | Treatment of liver disorders | YUHAN CORPORATION, LTD. (KR) | 1992-10-27 | — | — | US | disclosed |
| EP-0298040-A1 | 1,3-Dithiol-2-ylidene derivatives | YUHAN CORPORATION, LTD. (KR) | 1989-01-04 | — | — | EP | disclosed |