Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | GAA | P10253 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9706746 | 0.88 | CYP19A1 (0.49) | MAPTALDH1A1GAASMN1; SMN2CYP19A1 | |
| SCHEMBL9674962 | 0.87 | CYP19A1 (0.52) | MAPTALDH1A1SMN1; SMN2CYP19A1KDM4E | |
| SCHEMBL9674811 | 0.82 | ADRA1A (0.49) | MAPTALDH1A1GAASMN1; SMN2HTT | |
| SCHEMBL9706769 | 0.81 | ADRA1A (0.60) | MAPTALDH1A1GAASMN1; SMN2HTT | |
| SCHEMBL626949 | 0.81 | MAPT (0.73) | MAPTALDH1A1GAASMN1; SMN2HTT | |
| SCHEMBL9621031 | 0.77 | ADRA1A (0.55) | MAPTALDH1A1GAASMN1; SMN2HTT | |
| SCHEMBL11408843 | 0.74 | MAPT (0.83) | MAPTALDH1A1GAASMN1; SMN2HTT | |
| SCHEMBL8625994 | 0.73 | MAPT (0.61) | MAPTALDH1A1GAASMN1; SMN2HTT | |
| SCHEMBL9675401 | 0.73 | ADRA1A (0.60) | MAPTALDH1A1SMN1; SMN2TDP1KDM4E | |
| SCHEMBL9673076 | 0.73 | ALDH1A1 (0.45) | MAPTALDH1A1SMN1; SMN2KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5158950-A | Treatment of liver disorders | YUHAN CORPORATION, LTD. (KR) | 1992-10-27 | — | — | US | disclosed |
| EP-0298040-B1 | 1,3-DITHIOL-2-YLIDENE DERIVATIVES | YUHAN CORPORATION, LTD. (KR) | 1992-08-26 | — | — | EP | disclosed |
| EP-0298040-A1 | 1,3-Dithiol-2-ylidene derivatives | YUHAN CORPORATION, LTD. (KR) | 1989-01-04 | — | — | EP | disclosed |