Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9674380 | 0.92 | HPGD (0.44) | NPC1MAPTRAB9AALDH1A1MAPK1 | |
| SCHEMBL9675247 | 0.81 | ADRA1A (0.62) | NPC1MAPTRAB9AHPGDTSHR | |
| SCHEMBL11412912 | 0.80 | SMN1; SMN2 (0.57) | NPC1MAPTRAB9AALDH1A1MAPK1 | |
| SCHEMBL9865762 | 0.80 | SMN1; SMN2 (0.57) | NPC1MAPTRAB9AALDH1A1MAPK1 | |
| SCHEMBL20827027 | 0.78 | SMN1; SMN2 (0.54) | NPC1MAPTRAB9AALDH1A1MAPK1 | |
| SCHEMBL9621031 | 0.78 | ADRA1A (0.55) | MAPTALDH1A1TSHRKDM4ELMNA | |
| SCHEMBL24485231 | 0.75 | MAPT (0.48) | NPC1MAPTRAB9AALDH1A1MAPK1 | |
| SCHEMBL8531170 | 0.74 | ADRA1A (0.46) | MAPTALDH1A1KDM4ESMN1; SMN2GAA | |
| SCHEMBL11518690 | 0.72 | EPHX1 (0.51) | NPC1MAPTRAB9AALDH1A1MAPK1 | |
| SCHEMBL15294792 | 0.71 | EGLN1 (0.47) | NPC1MAPTRAB9AALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5158950-A | Treatment of liver disorders | YUHAN CORPORATION, LTD. (KR) | 1992-10-27 | — | — | US | disclosed |
| EP-0298040-A1 | 1,3-Dithiol-2-ylidene derivatives | YUHAN CORPORATION, LTD. (KR) | 1989-01-04 | — | — | EP | disclosed |