Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 1/20 | 0.62 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9706732 | 0.81 | ADRA1A (0.72) | ADRA1APDE4DSMN1; SMN2TSHR | |
| SCHEMBL9706748 | 0.81 | NPC1 (0.47) | SMN1; SMN2NPC1RAB9AMAPTHPGD | |
| SCHEMBL9706771 | 0.79 | ADRA1A (0.74) | ADRA1APDE4DSMN1; SMN2 | |
| Malotilate SCHEMBL635496 | 0.78 | ADRA1A (1.00) | ADRA1APDE4DSMN1; SMN2NPC1RAB9A | |
| SCHEMBL8055886 | 0.74 | ADRA1A (0.82) | ADRA1APDE4DSMN1; SMN2TSHR | |
| SCHEMBL9674380 | 0.74 | HPGD (0.44) | NPC1RAB9AMAPTHPGDTSHR | |
| SCHEMBL9706734 | 0.72 | ADRA1A (0.79) | ADRA1APDE4DSMN1; SMN2TSHR | |
| SCHEMBL9672860 | 0.72 | ADRA1A (0.62) | ADRA1APDE4DSMN1; SMN2NPC1RAB9A | |
| SCHEMBL9674429 | 0.71 | ADRA1A (0.66) | ADRA1APDE4DSMN1; SMN2NPC1RAB9A | |
| SCHEMBL19500088 | 0.71 | SMN1; SMN2 (0.41) | ADRA1APDE4DSMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5158950-A | Treatment of liver disorders | YUHAN CORPORATION, LTD. (KR) | 1992-10-27 | — | — | US | disclosed |
| EP-0298040-B1 | 1,3-DITHIOL-2-YLIDENE DERIVATIVES | YUHAN CORPORATION, LTD. (KR) | 1992-08-26 | — | — | EP | disclosed |