Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11016513 | 0.80 | RAB9A (0.46) | TDP1L3MBTL1ALDH1A1NPC1RAB9A | |
| SCHEMBL11574977 | 0.77 | NPC1 (0.50) | TDP1ALDH1A1NPC1RAB9AKMT2A | |
| SCHEMBL27521078 | 0.75 | L3MBTL1 (0.55) | EPHX1TDP1L3MBTL1ALDH1A1NPC1 | |
| SCHEMBL4963232 | 0.75 | TDP1 (0.46) | TDP1L3MBTL1ALDH1A1NPC1RAB9A | |
| SCHEMBL10784052 | 0.75 | ATM (0.48) | TDP1L3MBTL1ALDH1A1NPC1RAB9A | |
| SCHEMBL622873 | 0.73 | ATM (0.47) | TDP1L3MBTL1ALDH1A1NPC1RAB9A | |
| SCHEMBL2913044 | 0.73 | TDP1 (0.47) | EPHX1TDP1L3MBTL1ALDH1A1NPC1 | |
| SCHEMBL10626822 | 0.73 | TDP1 (0.47) | EPHX1TDP1L3MBTL1ALDH1A1NPC1 | |
| SCHEMBL3826087 | 0.72 | TDP1 (0.46) | TDP1L3MBTL1ALDH1A1KMT2AMEN1 | |
| SCHEMBL622872 | 0.72 | TDP1 (0.46) | TDP1L3MBTL1ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992012707-A1 | A BENZOYLUREA-CONTAINING COMPOSITION FOR PARASITE CONTROL IN ANIMALS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-08-06 | — | — | WO | disclosed |
| US-4897486-A | INSECTICIDES, MITICIDES, LARVICIDES | CIBA-GEIGY CORPORATION (US) | 1990-01-30 | — | — | US | disclosed |
| US-4687855-A | PESTICIDES; | CIBA-GEIGY CORPORATION (US) | 1987-08-18 | — | — | US | disclosed |
| US-4677127-A | Certain N-3-(3-chloro-5-trifluoromethyl-pyridyl-2-oxy)-4-phenyl-N'-2,6-difluorobenzoyl ureas, pesticidal compositions and methods of use | CIBA-GEIGY CORPORATION (US) | 1987-06-30 | — | — | US | disclosed |
| US-4418066-A | PESTICIDES | CIBA-GEIGY CORPORATION (US) | 1983-11-29 | — | — | US | disclosed |