Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CETP | P11597 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14268497 | 1.00 | ALDH1A1 (0.39) | ALDH1A1CYP2D6MAPK1PDPK1MTOR | |
| SCHEMBL9300189 | 1.00 | ALDH1A1 (0.39) | ALDH1A1CYP2D6MAPK1PDPK1MTOR | |
| SCHEMBL23563202 | 1.00 | ALDH1A1 (0.39) | ALDH1A1CYP2D6MAPK1PDPK1MTOR | |
| SCHEMBL8672177 | 0.90 | PDPK1 (0.37) | ALDH1A1CYP2D6MAPK1PDPK1MTOR | |
| SCHEMBL14268494 | 0.89 | SLC6A2 (0.39) | ALDH1A1PDPK1MTORTSHRCETP | |
| SCHEMBL13964785 | 0.87 | ALDH1A1 (0.39) | ALDH1A1CYP2D6MAPK1PDPK1MTOR | |
| SCHEMBL14268504 | 0.84 | TSHR (0.57) | ALDH1A1CYP2D6MAPK1TSHRLMNA | |
| SCHEMBL9548495 | 0.83 | TSHR (0.40) | ALDH1A1CYP2D6MAPK1TSHRLMNA | |
| SCHEMBL4820346 | 0.83 | TSHR (0.40) | ALDH1A1CYP2D6MAPK1TSHRLMNA | |
| SCHEMBL7566949 | 0.83 | TSHR (0.40) | ALDH1A1CYP2D6MAPK1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0502298-A2 | Process for the stereo-selective preparation of beta-fucopyranosyl phosphates and very pure GDP-fucose | MERCK PATENT GmbH (DE) | 1992-09-09 | — | — | EP | disclosed |