Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | P2RY10 | O00398 | 2/20 | 0.54 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.51 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.51 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.48 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.45 |
| ▸ | PRKCG | P05129 | 1/20 | 0.45 |
| ▸ | PRKCB | P05771 | 1/20 | 0.45 |
| ▸ | PRKCA | P17252 | 1/20 | 0.45 |
| ▸ | PRKCH | P24723 | 1/20 | 0.45 |
| ▸ | PRKCI | P41743 | 1/20 | 0.45 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.45 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.45 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.45 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.45 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.45 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9706845 | 1.00 | USP2 (0.56) | USP2HTTP2RY10LPAR1LPAR3 | |
| Hydrochloric Acid SCHEMBL2992402 | 0.90 | USP2 (0.67) | USP2HTTLPAR1LPAR3LPAR5 | |
| Hydrochloric Acid SCHEMBL9706804 | 0.90 | USP2 (0.67) | USP2HTTLPAR1LPAR3LPAR5 | |
| Hydrochloric Acid SCHEMBL9706808 | 0.90 | USP2 (0.67) | USP2HTTLPAR1LPAR3LPAR5 | |
| Hydrochloric Acid SCHEMBL9706783 | 0.90 | USP2 (0.67) | USP2HTTLPAR1LPAR3LPAR5 | |
| Hydrochloric Acid SCHEMBL6419460 | 0.90 | USP2 (0.67) | USP2HTTLPAR1LPAR3LPAR5 | |
| Hydrochloric Acid SCHEMBL9706829 | 0.90 | USP2 (0.67) | USP2HTTLPAR1LPAR3LPAR5 | |
| Hydrochloric Acid SCHEMBL9706811 | 0.90 | USP2 (0.67) | USP2HTTLPAR1LPAR3LPAR5 | |
| SCHEMBL2998598 | 0.89 | USP2 (0.65) | USP2HTTP2RY10LPAR1LPAR3 | |
| SCHEMBL20124691 | 0.89 | USP2 (0.65) | USP2HTTP2RY10LPAR1LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0222335-B1 | NON-BRONZING REDDISH LAKE PIGMENT | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1992-08-19 | — | — | EP | disclosed |
| US-4711674-A | SURFACE TREATMENT WITH N-(3-ALKOXY-2-HYDROXYPROPYL)TRIALKYL AMMONIUM SALT | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1987-12-08 | — | — | US | disclosed |
| EP-0222335-A2 | Non-bronzing reddish lake pigment | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1987-05-20 | — | — | EP | disclosed |