Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 3/20 | 0.47 |
| ▸ | LTB4R | Q15722 | 8/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.35 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9199172 | 0.90 | SCN9A (0.49) | SCN9ALTB4RLTB4R2HPGDHSD17B10 | |
| SCHEMBL9199187 | 0.90 | SCN9A (0.49) | SCN9ALTB4RLTB4R2HPGDHSD17B10 | |
| SCHEMBL8941305 | 0.80 | CYSLTR2 (0.53) | SCN9ALTB4RLTB4R2HPGDHSD17B10 | |
| SCHEMBL8941405 | 0.77 | SCN9A (0.48) | SCN9ALTB4RLTB4R2HPGDHSD17B10 | |
| SCHEMBL9706858 | 0.75 | LTB4R (0.55) | LTB4RLTB4R2LMNACYSLTR2CYSLTR1 | |
| SCHEMBL9195871 | 0.72 | LTB4R (0.49) | LTB4RLTB4R2KDM4ELMNACYSLTR2 | |
| SCHEMBL8957222 | 0.71 | CYSLTR2 (0.59) | LTB4RLMNACYSLTR2CYSLTR1 | |
| SCHEMBL8957035 | 0.68 | CYSLTR2 (0.51) | LTB4RHSD17B10LMNACYSLTR2CYSLTR1 | |
| SCHEMBL9694165 | 0.68 | LTB4R (0.46) | SCN9ALTB4RLTB4R2 | |
| SCHEMBL8941740 | 0.66 | LTB4R (0.69) | LTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992000011-A2 | LEUKOTRIENE B4 ANTAGONISTS | G.D. SEARLE & CO. (US) | 1992-01-09 | — | — | WO | claimed |