SCHEMBL9706878

SCHEMBL9706878

C=C(C)C(=O)OCCCC[SiH2]O[SiH3]

nearest known ligand 0.56

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.56
THRB P10828 1/20 0.44
POLB P06746 1/20 0.43
APEX1 P27695 1/20 0.43
HTT P42858 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
ALDH1A1 P00352 3/20 0.38
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1155455 0.95 TSHR (0.53) TSHRTHRBPOLBAPEX1HTT
SCHEMBL15161769 0.87 THRB (0.48) TSHRTHRBPOLBAPEX1HTT
SCHEMBL10942181 0.87 TSHR (0.44) TSHRTHRBPOLBAPEX1HTT
SCHEMBL8766935 0.86 TSHR (0.59) TSHRTHRBPOLBAPEX1HTT
SCHEMBL3898618 0.84 TSHR (0.58) TSHRTHRBPOLBAPEX1HTT
SCHEMBL29035611 0.83 TSHR (0.61) TSHRTHRBPOLBAPEX1HTT
SCHEMBL21694103 0.82 TSHR (0.59) TSHRTHRBPOLBAPEX1HTT
SCHEMBL29173969 0.82 TSHR (0.47) TSHRTHRBPOLBAPEX1HTT
SCHEMBL5144090 0.81 TSHR (0.79) TSHRTHRBPOLBAPEX1HTT
SCHEMBL25426 0.81 TSHR (0.79) TSHRTHRBPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4308520-B1 ISOCYANATE-AMINO-BASED CHEMICAL DOWEL WITH IMPROVED PERFORMANCE AND ITS USE HILTI AG (LI) 2025-01-15 EP claimed
US-20240166870-A1 ISOCYANATE-AMINE-BASED CHEMICAL ANCHOR WITH IMPROVED PERFORMANCE, AND USE THEREOF HILTI AKTIENGESELLSCHAFT (LI) 2024-05-23 US claimed
US-11525962-B2 Optical fiber alignment device with self-healing refractive index-matching gel of polysiloxane and method of making COMMSCOPE TECHNOLOGIES LLC (US) 2022-12-13 US disclosed
US-20210356676-A1 OPTICAL FIBER ALIGNMENT DEVICE WITH SELF-HEALING REFRACTIVE INDEX-MATCHING GEL COMMSCOPE TECHNOLOGIES LLC (US) 2021-11-18 US disclosed
US-11054583-B2 Optical fiber alignment device with self-healing refractive index-matching gel COMMSCOPE TECHNOLOGIES LLC (US) 2021-07-06 US disclosed
US-20200116947-A1 OPTICAL FIBER ALIGNMENT DEVICE WITH SELF-HEALING REFRACTIVE INDEX-MATCHING GEL COMMSCOPE TECHNOLOGIES LLC (US) 2020-04-16 US disclosed
EP-3635461-A1 OPTICAL FIBER ALIGNMENT DEVICE WITH SELF-HEALING REFRACTIVE INDEX-MATCHING GEL Commscope Technologies LLC (US) 2020-04-15 EP disclosed
WO-2018226872-A1 OPTICAL FIBER ALIGNMENT DEVICE WITH SELF-HEALING REFRACTIVE INDEX-MATCHING GEL COMMSCOPE TECHNOLOGIES LLC (US) 2018-12-13 WO disclosed
US-5079300-A Curable Gel RAYCHEM CORPORATION (US) 1992-01-07 US disclosed
EP-0461185-A1 METHOD OF CURING ORGANOPOLYSILOXANE COMPOSITIONS AND COMPOSITIONS AND ARTICLES THEREFROM RAYCHEM CORPORATION (US) 1991-12-18 EP disclosed
WO-1990010035-A1 METHOD OF CURING ORGANOPOLYSILOXANE COMPOSITIONS AND COMPOSITIONS AND ARTICLES THEREFROM RAYCHEM CORPORATION (US) 1990-09-07 WO disclosed