Oxyfluorfen

Oxyfluorfen

SCHEMBL9706928

CC(C)Oc1cc(-n2nc(C(C)(C)C)oc2=O)c(Cl)cc1Cl.CC(C)Oc1cc(-n2nc(C(C)(C)C)oc2=O)c(Cl)cc1Cl.CCOc1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-].CCOc1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-]

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PPOX P50336 14/20 0.55
MEN1 O00255 3/20 0.55
KMT2A Q03164 3/20 0.55
TDP1 Q9NUW8 2/20 0.55
NR1I2 O75469 1/20 0.55
TTR P02766 1/20 0.42
ALDH1A1 P00352 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C19 P33261 1/20 0.33
KDM4E B2RXH2 2/20 0.33
HPGD P15428 1/20 0.33
MAPT P10636 1/20 0.33
CYP2C9 P11712 1/20 0.33
MAPK1 P28482 1/20 0.33
FFAR1 O14842 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxyfluorfen SCHEMBL7577811 1.00 PPOX (0.55) PPOXMEN1KMT2ATDP1NR1I2
Oxyfluorfen SCHEMBL7576247 0.89 PPOX (0.41) PPOXMEN1KMT2ATDP1NR1I2
Oxyfluorfen SCHEMBL10336539 0.89 PPOX (0.44) PPOXMEN1KMT2ATDP1NR1I2
Acifluorfen SCHEMBL7575230 0.88 PPOX (0.59) PPOXMEN1KMT2ATDP1NR1I2
Oxadiazon SCHEMBL7576763 0.86 PPOX (0.49) PPOXMEN1KMT2ATDP1NR1I2
Lactofen SCHEMBL7574560 0.86 PPOX (0.49) PPOXMEN1KMT2ATDP1NR1I2
Fomesafen SCHEMBL7577915 0.84 PPOX (0.51) PPOXMEN1KMT2ATDP1NR1I2
Oxyfluorfen SCHEMBL7578497 0.83 MEN1 (0.57) PPOXMEN1KMT2ATDP1NR1I2
Acifluorfen SCHEMBL7578056 0.79 PPOX (0.56) PPOXMEN1KMT2ATDP1NR1I2
Lactofen SCHEMBL7580054 0.79 PPOX (0.43) PPOXMEN1KMT2ATDP1NR1I2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1992010501-A1 HERBICIDAL ETHERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-06-25 WO disclosed
WO-1992009587-A1 HERBICIDAL OXAZINE ETHERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-06-11 WO disclosed