Lactofen

Lactofen

SCHEMBL7574560

CC(C)Oc1cc(-n2nc(C(C)(C)C)oc2=O)c(Cl)cc1Cl.CCOC(=O)C(C)OC(=O)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-]

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PPOX P50336 16/20 0.49
TDP1 Q9NUW8 3/20 0.49
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
NR1I2 O75469 1/20 0.49
TTR P02766 1/20 0.46
PPARD Q03181 1/20 0.33
FFAR1 O14842 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxadiazon SCHEMBL7576763 0.92 PPOX (0.49) PPOXTDP1MEN1KMT2ANR1I2
Lactofen SCHEMBL7580054 0.91 PPOX (0.43) PPOXTDP1MEN1KMT2ANR1I2
Acifluorfen SCHEMBL7575230 0.89 PPOX (0.59) PPOXTDP1MEN1KMT2ANR1I2
Oxyfluorfen SCHEMBL7577811 0.86 PPOX (0.55) PPOXTDP1MEN1KMT2ANR1I2
Oxyfluorfen SCHEMBL9706928 0.86 PPOX (0.55) PPOXTDP1MEN1KMT2ANR1I2
Fomesafen SCHEMBL7577915 0.85 PPOX (0.51) PPOXTDP1MEN1KMT2ANR1I2
Oxadiazon SCHEMBL7588134 0.84 PPOX (0.56) PPOXTDP1MEN1KMT2ANR1I2
Lactofen SCHEMBL8536001 0.82 MEN1 (0.66) PPOXTDP1MEN1KMT2ATTR
Lactofen SCHEMBL29462400 0.82 MEN1 (0.66) PPOXTDP1MEN1KMT2ATTR
Lactofen SCHEMBL30359837 0.82 MEN1 (0.66) PPOXTDP1MEN1KMT2ATTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT PPOX 1/4885TDP1 1969/4885MEN1 4274/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.