Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 2/20 | 0.41 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | MDM4 | O15151 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4395836 | 1.00 | KMT2A (0.45) | KMT2AMEN1MDM2CASP3FABP5 | |
| SCHEMBL12555211 | 0.95 | KMT2A (0.47) | KMT2AMEN1MDM2CASP3FABP5 | |
| SCHEMBL17192730 | 0.92 | KMT2A (0.45) | KMT2AMEN1MDM2CASP3FABP5 | |
| SCHEMBL8410923 | 0.92 | KMT2A (0.45) | KMT2AMEN1MDM2CASP3FABP5 | |
| SCHEMBL12873284 | 0.91 | LMNA (0.46) | KMT2AMEN1MDM2CASP3FABP5 | |
| SCHEMBL1623874 | 0.91 | KMT2A (0.44) | KMT2AMEN1MDM2CASP3FABP5 | |
| SCHEMBL12588064 | 0.89 | KMT2A (0.42) | KMT2AMEN1MDM2CASP3FABP5 | |
| SCHEMBL3367289 | 0.89 | KMT2A (0.45) | KMT2AMEN1MDM2CASP3FABP5 | |
| SCHEMBL16316701 | 0.89 | KMT2A (0.42) | KMT2AMEN1MDM2CASP3FABP5 | |
| SCHEMBL14416300 | 0.89 | KMT2A (0.42) | KMT2AMEN1MDM2CASP3FABP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992010515-A1 | DERIVATES OF THE HUMAN PARATHORMONE FRAGMENT (1-37) IN THE AMIDE OR ETHYLAMIDE FORM AS ACTIVE SUBSTANCE | PHARMA BISSENDORF PEPTIDE GMBH (DE) | 1992-06-25 | — | — | WO | disclosed |