SCHEMBL9707040

SCHEMBL9707040

O=[Si](O)OCCOc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 2/20 0.53
KCNA3 P22001 1/20 0.52
ALDH1A1 P00352 3/20 0.52
RECQL P46063 1/20 0.52
PARP10 Q53GL7 1/20 0.50
RAB9A P51151 4/20 0.47
THRB P10828 1/20 0.47
MAPT P10636 1/20 0.47
TAAR1 Q96RJ0 1/20 0.47
NPC1 O15118 3/20 0.46
SMN1; SMN2 Q16637 3/20 0.46
TSHR P16473 1/20 0.46
ALOX15 P16050 1/20 0.45
MTNR1A P48039 1/20 0.44
MTNR1B P49286 1/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
HPGD P15428 2/20 0.44
KDM4E B2RXH2 1/20 0.44
NFKB1 P19838 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9707038 0.83 KCNA3 (0.56) PKMKCNA3ALDH1A1RECQLPARP10
SCHEMBL27962 0.78 KCNA3 (0.82) PKMKCNA3ALDH1A1RECQLPARP10
SCHEMBL6030010 0.73 TDP1 (0.47) ALDH1A1RAB9AMAPTNPC1SMN1; SMN2
Ethylene SCHEMBL29058163 0.73 KCNA3 (0.74) PKMKCNA3ALDH1A1RECQLPARP10
SCHEMBL5697817 0.72 KCNA3 (0.64) PKMKCNA3ALDH1A1RECQLPARP10
SCHEMBL5697816 0.72 KCNA3 (0.64) PKMKCNA3ALDH1A1RECQLPARP10
SCHEMBL10877978 0.71 L3MBTL1 (0.66) PKMKCNA3ALDH1A1RECQLPARP10
SCHEMBL288156 0.71 THRB (0.65) PKMKCNA3ALDH1A1RECQLPARP10
SCHEMBL4900332 0.71 THRB (0.65) PKMKCNA3ALDH1A1RECQLPARP10
Bicarbonate SCHEMBL2031332 0.71 PARP10 (0.63) PKMKCNA3ALDH1A1RECQLPARP10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0516855-A1 POLYISOCYANATE COMPOSITION DOW MITSUBISHI KASEI LIMITED (JP) 1992-12-09 EP disclosed