Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.51 |
| ▸ | CES1 | P23141 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8886254 | 0.94 | CES2 (0.53) | CES2CES1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL5929946 | 0.80 | TSHR (0.57) | CES1ALDH1A1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL118227 | 0.80 | CES2 (0.77) | CES2CES1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL11135957 | 0.77 | FFAR1 (0.49) | ALDH1A1MAPTSMN1; SMN2RAB9AHTT | |
| Dimethylamine SCHEMBL6131311 | 0.77 | CES2 (0.67) | CES2CES1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL11147966 | 0.77 | ALDH1A1 (0.52) | ALDH1A1MAPTSMN1; SMN2RAB9AGAA | |
| SCHEMBL6408009 | 0.77 | CYP2C9 (0.56) | CES2CES1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL15075994 | 0.76 | POLB (0.59) | CES2CES1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL15075993 | 0.76 | POLB (0.59) | CES2CES1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL15076001 | 0.76 | POLB (0.59) | CES2CES1ALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992015579-A1 | MULTICYCLIC TERTIARY AMINE POLYAROMATIC SQUALENE SYNTHETASE INHIBITORS | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1992-09-17 | — | — | WO | disclosed |