Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 2/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL306600 | 0.93 | MLYCD (0.60) | MLYCDSMN1; SMN2CYP1A2KMT2AMEN1 | |
| SCHEMBL870352 | 0.91 | MLYCD (0.57) | MLYCDSMN1; SMN2KMT2AMEN1TDP1 | |
| SCHEMBL9152657 | 0.86 | MLYCD (0.53) | MLYCDSMN1; SMN2KMT2AMEN1TDP1 | |
| SCHEMBL13694024 | 0.77 | MLYCD (0.48) | MLYCDSMN1; SMN2CYP1A2ALDH1A1HSD17B10 | |
| SCHEMBL3716405 | 0.76 | MLYCD (0.43) | MLYCDCES2CES1 | |
| SCHEMBL1012521 | 0.76 | MLYCD (0.57) | MLYCDSMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL22531823 | 0.76 | MLYCD (0.57) | MLYCDSMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL1303906 | 0.76 | MLYCD (0.57) | MLYCDSMN1; SMN2KMT2AMEN1TDP1 | |
| SCHEMBL4568350 | 0.75 | MLYCD (0.49) | MLYCDKMT2AMEN1LMNAL3MBTL1 | |
| SCHEMBL5776326 | 0.75 | HDAC1 (0.51) | MLYCDKMT2AALDH1A1LMNACES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992015579-A1 | MULTICYCLIC TERTIARY AMINE POLYAROMATIC SQUALENE SYNTHETASE INHIBITORS | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1992-09-17 | — | — | WO | disclosed |