Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7631340 | 0.84 | AGTR1 (0.47) | AGTR1AGTR2 | |
| SCHEMBL7621887 | 0.83 | — | — | |
| SCHEMBL8412607 | 0.79 | AGTR1 (0.43) | AGTR1AGTR2 | |
| SCHEMBL181 | 0.74 | AGTR1 (0.73) | AGTR1AGTR2 | |
| SCHEMBL8981377 | 0.73 | AGTR1 (0.36) | AGTR1AGTR2 | |
| SCHEMBL7623723 | 0.73 | — | — | |
| SCHEMBL7623709 | 0.70 | — | — | |
| SCHEMBL9594806 | 0.69 | — | — | |
| SCHEMBL7628739 | 0.69 | AGTR1 (0.64) | AGTR1AGTR2 | |
| SCHEMBL7623321 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992015577-A1 | N-SUBSTITUTED (ALPHA-IMIDAZOLYL-TOLUYL) PYRROLE ANGIOTENSIN II ANTAGONISTS FOR TREATMENT OF CIRCULATORY DISORDERS | G.D. SEARLE & CO. (US) | 1992-09-17 | — | — | WO | claimed |
| WO-1992015577-A1 | N-SUBSTITUTED (ALPHA-IMIDAZOLYL-TOLUYL) PYRROLE ANGIOTENSIN II ANTAGONISTS FOR TREATMENT OF CIRCULATORY DISORDERS | G.D. SEARLE & CO. (US) | 1992-09-17 | — | — | WO | disclosed |