Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | FYN | P06241 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | AHR | P35869 | 2/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4421747 | 0.90 | ALDH1A1 (0.46) | HPRT1ALDH1A1HSD17B10TDP1CYP2A6 | |
| SCHEMBL8714223 | 0.81 | HPRT1 (0.50) | HPRT1ALDH1A1HSD17B10TDP1CYP2A6 | |
| SCHEMBL31456577 | 0.81 | HPRT1 (0.50) | HPRT1ALDH1A1HSD17B10TDP1CYP2A6 | |
| Hydrochloric Acid SCHEMBL8713800 | 0.80 | HPRT1 (0.48) | HPRT1ALDH1A1HSD17B10TDP1CYP2A6 | |
| SCHEMBL21187674 | 0.79 | HPRT1 (0.47) | HPRT1ALDH1A1HSD17B10TDP1CYP2A6 | |
| SCHEMBL28889640 | 0.76 | HSD17B10 (0.39) | HPRT1ALDH1A1HSD17B10TDP1CYP2A6 | |
| Chrysene SCHEMBL27115 | 0.73 | HPRT1 (1.00) | HPRT1ALDH1A1HSD17B10TDP1CYP2A6 | |
| Chrysene SCHEMBL384031 | 0.73 | HPRT1 (1.00) | HPRT1ALDH1A1HSD17B10TDP1CYP2A6 | |
| SCHEMBL31177955 | 0.73 | HPRT1 (1.00) | HPRT1ALDH1A1HSD17B10TDP1CYP2A6 | |
| Chrysene SCHEMBL9786466 | 0.73 | HPRT1 (1.00) | HPRT1ALDH1A1HSD17B10TDP1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992007855-A1 | TETRACYCLIC AMINES HAVING PHARMACEUTICAL ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1992-05-14 | — | — | WO | disclosed |