Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11275867 | 0.79 | — | — | |
| SCHEMBL2159026 | 0.68 | KDM4E (0.34) | KDM4EPOLBL3MBTL1 | |
| SCHEMBL11702792 | 0.64 | — | — | |
| SCHEMBL821855 | 0.64 | — | — | |
| Hydrazine SCHEMBL1572402 | 0.62 | KDM1A (0.30) | — | |
| SCHEMBL5378612 | 0.62 | — | — | |
| SCHEMBL15466836 | 0.60 | — | — | |
| SCHEMBL9630842 | 0.57 | POLB (0.43) | KDM4EPOLBL3MBTL1 | |
| SCHEMBL5709302 | 0.57 | ALDH1A1 (0.35) | KDM4E | |
| SCHEMBL5709301 | 0.57 | ALDH1A1 (0.35) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992007855-A1 | TETRACYCLIC AMINES HAVING PHARMACEUTICAL ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1992-05-14 | — | — | WO | disclosed |