Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 11/20 | 0.50 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29607922 | 0.80 | HTR2A (0.39) | SIGMAR1 | |
| SCHEMBL8130206 | 0.80 | HTR2A (0.39) | SIGMAR1 | |
| SCHEMBL1366559 | 0.79 | SIGMAR1 (0.45) | SIGMAR1IDO1PDPK1SRD5A1 | |
| SCHEMBL2767254 | 0.78 | SIGMAR1 (0.54) | SIGMAR1IDO1PDPK1SRD5A1 | |
| SCHEMBL11671198 | 0.77 | SRD5A1 (0.55) | SIGMAR1IDO1PDPK1SRD5A1 | |
| SCHEMBL19100019 | 0.76 | PDPK1 (0.46) | SIGMAR1IDO1PDPK1SRD5A1 | |
| SCHEMBL8077660 | 0.76 | IDO1 (0.42) | SIGMAR1IDO1PDPK1 | |
| Magnesium SCHEMBL31510119 | 0.74 | SRD5A1 (0.53) | SIGMAR1IDO1PDPK1SRD5A1 | |
| SCHEMBL2064332 | 0.74 | SIGMAR1 (0.56) | SIGMAR1 | |
| SCHEMBL9294850 | 0.74 | SIGMAR1 (0.56) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992007855-A1 | TETRACYCLIC AMINES HAVING PHARMACEUTICAL ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1992-05-14 | — | — | WO | disclosed |