SCHEMBL19100019

SCHEMBL19100019

C1=CC2CCc3ccccc3C2C1

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PDPK1 O15530 1/20 0.46
IDO1 P14902 2/20 0.42
SIGMAR1 Q99720 3/20 0.41
SRD5A1 P18405 3/20 0.41
KDM1A O60341 1/20 0.41
MAOA P21397 1/20 0.41
MAOB P27338 1/20 0.41
CYP11B2 P19099 2/20 0.40
CYP17A1 P05093 1/20 0.39
CYP19A1 P11511 1/20 0.39
HTR1A P08908 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9707381 0.76 SIGMAR1 (0.50) PDPK1IDO1SIGMAR1SRD5A1
SCHEMBL11671198 0.75 SRD5A1 (0.55) PDPK1IDO1SIGMAR1SRD5A1CYP11B2
SCHEMBL30955924 0.74 IDO1 (0.44) IDO1SIGMAR1CYP19A1HTR1A
Magnesium SCHEMBL31510119 0.73 SRD5A1 (0.53) PDPK1IDO1SIGMAR1SRD5A1CYP11B2
SCHEMBL12274324 0.73 SIGMAR1 (0.41) PDPK1IDO1SIGMAR1SRD5A1CYP11B2
SCHEMBL6267631 0.73 SRD5A1 (0.43) PDPK1IDO1SIGMAR1SRD5A1KDM1A
SCHEMBL8077660 0.70 IDO1 (0.42) PDPK1IDO1SIGMAR1CYP11B2
SCHEMBL1366559 0.70 SIGMAR1 (0.45) PDPK1IDO1SIGMAR1SRD5A1
SCHEMBL2257434 0.69 SIGMAR1 (0.41) PDPK1IDO1SIGMAR1SRD5A1CYP11B2
SCHEMBL2767254 0.68 SIGMAR1 (0.54) PDPK1IDO1SIGMAR1SRD5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11040995-B2 Catalyst comprising a metallocene complex and co-catalyst SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2021-06-22 US claimed
US-20200270292-A1 CATALYST COMPRISING A METALLOCENE COMPLEX AND CO-CATALYST SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2020-08-27 US claimed
EP-3400230-B1 CATALYST COMPRISING A METALLOCENE COMPLEX AND A CO-CATALYST SABIC GLOBAL TECHNOLOGIES BV (NL) 2019-09-11 EP claimed
EP-3400230-A1 CATALYST COMPRISING A METALLOCENE COMPLEX AND A CO-CATALYST SABIC Global Technologies B.V. (NL) 2018-11-14 EP claimed
WO-2017118617-A1 CATALYST COMPRISING A METALLOCENE COMPLEX AND A CO-CATALYST SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2017-07-13 WO claimed
US-12503529-B2 Polymers of 4-substituted hexadiene and processes for production thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2025-12-23 US disclosed
EP-4587487-A2 CATALYST SYSTEMS AND PROCESSES FOR CYCLIC POLY ALPHA-OLEFINS ExxonMobil Technology and Engineering Company (US) 2025-07-23 EP disclosed
US-12344696-B2 Process to produce low viscosity polyalphaolefins using non-aromatic-hydrocarbon soluble activators EXXONMOBIL CHEMICAL PATENTS INC. (US) 2025-07-01 US disclosed
EP-4010385-B1 PROCESS TO PRODUCE LOW VISCOSITY POLYALPHAOLEFINS USING NON-AROMATIC-HYDROCARBON SOLUBLE ACTIVATORS EXXONMOBIL CHEMICAL PATENTS INC (US) 2025-01-22 EP disclosed
US-12195563-B2 Polyolefin-based ionomers and production thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2025-01-14 US disclosed
US-20240317905-A1 POLYMERS OF VINYLCYCLOBUTANE AND PROCESSES FOR MAKING SAME EXXONMOBIL CHEMICAL PATENTS INC. 2024-09-26 US disclosed
US-20240239929-A1 Biphasic Polymerization Processes EXXONMOBIL CHEMICAL PATENTS INC (US) 2024-07-18 US disclosed
US-20210107930-A1 Indacene Based Metallocene Catalysts Useful in the Production of Propylene Polymers EXXONMOBIL CHEMICAL PATENTS INC. 2021-04-15 US disclosed
WO-2021030045-A1 PROCESS TO PRODUCE LOW VISCOSITY POLYALPHAOLEFINS USING NON-AROMATIC-HYDROCARBON SOLUBLE ACTIVATORS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2021-02-18 WO disclosed
US-20200270292-A1 CATALYST COMPRISING A METALLOCENE COMPLEX AND CO-CATALYST SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2020-08-27 US disclosed
WO-2020112553-A1 BLENDS OF CYCLIC OLEFIN COPOLYMERS AND FILMS PREPARED THEREFROM EXXONMOBIL CHEMICAL PATENTS INC. (US) 2020-06-04 WO disclosed
US-20200172715-A1 Blends of Cyclic Olefin Copolymers and Films Prepared Therefrom EXXONMOBIL CHEMICAL PATENTS INC. 2020-06-04 US disclosed
EP-3400230-B1 CATALYST COMPRISING A METALLOCENE COMPLEX AND A CO-CATALYST SABIC GLOBAL TECHNOLOGIES BV (NL) 2019-09-11 EP disclosed
EP-3400230-A1 CATALYST COMPRISING A METALLOCENE COMPLEX AND A CO-CATALYST SABIC Global Technologies B.V. (NL) 2018-11-14 EP disclosed
WO-2017118617-A1 CATALYST COMPRISING A METALLOCENE COMPLEX AND A CO-CATALYST SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2017-07-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11040995-B2 Catalyst comprising a metallocene complex and co-catalyst CCRL2, UBE2L3, MAL2 PDPK1 3955/4885IDO1 2031/4885SIGMAR1 281/4885
US-20200270292-A1 CATALYST COMPRISING A METALLOCENE COMPLEX AND CO-CATALYST LAS1L, CCNE2, CKS2 PDPK1 4108/4885IDO1 2042/4885SIGMAR1 525/4885
US-20210107930-A1 Indacene Based Metallocene Catalysts Useful in the Production of Propylene Polymers INF2, INTS6, PORCN PDPK1 1206/4885IDO1 31/4885SIGMAR1 1355/4885
US-12344696-B2 Process to produce low viscosity polyalphaolefins using non-aromatic-hydrocarbon soluble activators NONO, F2, SCO2 PDPK1 1337/4885IDO1 497/4885SIGMAR1 1328/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.