Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | ACP3 | P15309 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL477450 | 0.88 | L3MBTL1 (0.52) | POLBKMT2AESR2PKMPTPN1 | |
| SCHEMBL477460 | 0.88 | L3MBTL1 (0.52) | POLBKMT2AESR2PKMPTPN1 | |
| SCHEMBL3585861 | 0.79 | CA12 (0.59) | CA12CA1CA2CA9CA14 | |
| SCHEMBL2719370 | 0.79 | CYP11B1 (0.56) | POLBKMT2AESR2PKMPTPN1 | |
| SCHEMBL24516966 | 0.78 | KMT2A (0.42) | POLBKMT2AESR2PKMPTPN1 | |
| SCHEMBL4504963 | 0.77 | CA1 (0.62) | L3MBTL1CA12CA1CA2CA9 | |
| SCHEMBL7684954 | 0.76 | KMT2A (0.56) | POLBKMT2AESR2PKMPTPN1 | |
| SCHEMBL24516523 | 0.74 | GAA (0.47) | POLBKMT2APKML3MBTL1HSD17B10 | |
| SCHEMBL24515979 | 0.74 | UGT2B7 (0.52) | POLBKMT2AESR2PKMPTPN1 | |
| SCHEMBL8925746 | 0.74 | CA1 (0.64) | L3MBTL1CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992011762-A1 | FUNGICIDAL HYDROXYPYRANONES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-07-23 | — | — | WO | disclosed |