SCHEMBL477450

SCHEMBL477450

OC(c1ccccc1)c1ccco1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.52
KMT2A Q03164 3/20 0.52
POLB P06746 3/20 0.52
PKM P14618 1/20 0.52
PTPN1 P18031 1/20 0.52
PTPN7 P35236 1/20 0.52
BLM P54132 1/20 0.52
ESR2 Q92731 1/20 0.52
CYP2C19 P33261 1/20 0.50
HSD17B10 Q99714 1/20 0.48
HPGD P15428 2/20 0.44
RECQL P46063 2/20 0.44
GLA P06280 1/20 0.44
LMNA P02545 1/20 0.43
MEN1 O00255 2/20 0.42
AGTR1 P30556 1/20 0.42
ALDH1A1 P00352 6/20 0.42
SMN1; SMN2 Q16637 1/20 0.41
MIF P14174 1/20 0.41
MAPT P10636 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL477460 1.00 L3MBTL1 (0.52) L3MBTL1KMT2APOLBPKMPTPN1
SCHEMBL9707878 0.88 POLB (0.46) L3MBTL1KMT2APOLBPKMPTPN1
SCHEMBL7684954 0.83 KMT2A (0.56) L3MBTL1KMT2APOLBPKMPTPN1
SCHEMBL24516966 0.81 KMT2A (0.42) L3MBTL1KMT2APOLBPKMPTPN1
SCHEMBL23089955 0.78 KMT2A (0.48) L3MBTL1KMT2APOLBPKMPTPN1
SCHEMBL24515979 0.77 UGT2B7 (0.52) L3MBTL1KMT2APOLBPKMPTPN1
SCHEMBL24516523 0.77 GAA (0.47) L3MBTL1KMT2APOLBPKMCYP2C19
SCHEMBL1934617 0.76 CYP2C19 (0.48) L3MBTL1KMT2APOLBPKMPTPN1
SCHEMBL8627683 0.76 CYP2C19 (0.48) L3MBTL1KMT2APOLBPKMPTPN1
SCHEMBL23089951 0.75 KMT2A (0.46) L3MBTL1KMT2APOLBPKMPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101210017-A Synthesis of middle position-tetraaryldiphenanthrene dioxyporphyrin derivative and application thereof NANJING UNIVERSITY OF TECHNOLOGY (CN) 2008-07-02 CN claimed
CN-115066428-B Boric acid derivatives 首药控股(北京)股份有限公司 2025-06-13 CN disclosed
CN-115413657-A Application of cinnamic acid derivative in mosquito control 五邑大学 2022-12-02 CN disclosed
WO-2022122975-A1 CYCLOPENTENONES DERIVATIVES AND THEIR USE AS ANTIBIOTICS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2022-06-16 WO disclosed
CN-112264089-B SAPO-11 Ni-loaded composite catalyst and preparation method and application thereof 江南大学 2021-11-23 CN disclosed
CN-112264089-A SAPO-11 Ni-loaded composite catalyst and preparation method and application thereof 江南大学 2021-01-26 CN disclosed
CN-109180624-A A kind of preparation method of novel 6- hydroxyl -2H- pyrans -3- ketone 大连理工大学 2019-01-11 CN disclosed
US-8563786-B2 Method for producing optically active alcohol MITSUI CHEMICALS, INC. (JP) 2013-10-22 US disclosed
US-20120088938-A1 METHOD FOR PRODUCING OPTICALLY ACTIVE ALCOHOL AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2012-04-12 US disclosed
EP-2412694-A1 PROCESS FOR PRODUCING OPTICALLY ACTIVE ALCOHOL Mitsui Chemicals, Inc. (JP) 2012-02-01 EP disclosed
CN-101210017-A Synthesis of middle position-tetraaryldiphenanthrene dioxyporphyrin derivative and application thereof NANJING UNIVERSITY OF TECHNOLOGY (CN) 2008-07-02 CN disclosed
US-6211374-B1 REVERSE COLOR CHANGE; DISPLAYING IPPOLITI JOSEPH THOMAS (US) 2001-04-03 US disclosed
US-4536349-A Furan derivatives useful as aroma compounds NATIONAL DISTILLERS AND CHEMICAL CORPORATION (US) 1985-08-20 US disclosed
US-4496767-A REARRANGEMENT, ESTERIFICATION AND REDUCTION OF A FURAN-CARBINOL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-01-29 US disclosed
US-4246178-A CHEMICAL INTERMEDIATE FOR THE FLAVOR MALTOL SHIN-ETSU CHEMICAL CO., LTD. (JP) 1981-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120088938-A1 METHOD FOR PRODUCING OPTICALLY ACTIVE ALCOHOL ADH1A, ADH1C, FHIT L3MBTL1 4093/4885KMT2A 1166/4885POLB 1884/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.