Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | THPO | P40225 | 1/20 | 0.30 |
| ▸ | STAT6 | P42226 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7745020 | 0.75 | — | — | |
| SCHEMBL28281980 | 0.75 | MAPK1 (0.33) | MAPK1TP53NFKB1CYP2C19THPO | |
| SCHEMBL9708890 | 0.74 | — | — | |
| SCHEMBL8397241 | 0.74 | ATM (0.37) | CYP2C19LMNA | |
| SCHEMBL6983611 | 0.71 | MEN1 (0.31) | CYP2C19 | |
| SCHEMBL11744095 | 0.70 | — | — | |
| SCHEMBL10207658 | 0.69 | — | — | |
| SCHEMBL11744564 | 0.67 | — | — | |
| SCHEMBL28845941 | 0.67 | APLNR (0.34) | CYP2C19PMP22 | |
| SCHEMBL7749699 | 0.67 | APLNR (0.34) | CYP2C19PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102633767-A | Preparation method of non-ionic type iodine contrast medium intermediate 2-isopropyl-5-carboxy-1, 3-dioxane | WUHAN INST TECHNOLOGY | 2012-08-15 | — | — | CN | claimed |
| EP-0220034-B1 | MALONATE DERIVATIVES USEFUL AS LIGHT STABILIZERS FOR PLASTICS | ICI AMERICAS INC. (US) | 1992-06-24 | — | — | EP | claimed |
| US-4701485-A | Malonate-based light stabilizers for plastics | ICI AMERICAS INC. (US) | 1987-10-20 | — | — | US | claimed |
| CN-108929304-B | Preparation method of trans-2-substituent-5-carboxyl-1, 3-dioxane | 正大天晴药业集团股份有限公司 | 2022-09-20 | — | — | CN | disclosed |
| CN-102633767-B | Preparation method of non-ionic type iodine contrast medium intermediate 2-isopropyl-5-carboxy-1, 3-dioxane | WUHAN INST TECHNOLOGY | 2013-10-30 | — | — | CN | disclosed |
| CN-102633767-B | Preparation method of non-ionic type iodine contrast medium intermediate 2-isopropyl-5-carboxy-1, 3-dioxane | WUHAN INST TECHNOLOGY | 2013-10-30 | — | — | CN | disclosed |
| CN-102633767-A | Preparation method of non-ionic type iodine contrast medium intermediate 2-isopropyl-5-carboxy-1, 3-dioxane | WUHAN INST TECHNOLOGY | 2012-08-15 | — | — | CN | disclosed |
| CN-102633767-A | Preparation method of non-ionic type iodine contrast medium intermediate 2-isopropyl-5-carboxy-1, 3-dioxane | WUHAN INST TECHNOLOGY | 2012-08-15 | — | — | CN | disclosed |
| EP-0220034-B1 | MALONATE DERIVATIVES USEFUL AS LIGHT STABILIZERS FOR PLASTICS | ICI AMERICAS INC. (US) | 1992-06-24 | — | — | EP | disclosed |
| US-4701485-A | Malonate-based light stabilizers for plastics | ICI AMERICAS INC. (US) | 1987-10-20 | — | — | US | disclosed |
| EP-0220034-A2 | Malonate derivatives useful as light stabilizers for plastics | ICI AMERICAS INC. (US) | 1987-04-29 | — | — | EP | disclosed |