Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8400790 | 0.80 | ATM (0.33) | ATMALDH1A1 | |
| SCHEMBL6232003 | 0.77 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL30343256 | 0.76 | ATM (0.37) | ATMPOLBALDH1A1LMNAHSD17B10 | |
| SCHEMBL9708702 | 0.74 | MAPK1 (0.30) | CYP2C19LMNA | |
| SCHEMBL8038682 | 0.73 | POLB (0.35) | ATMCYP3A4CYP2C19POLBGAA | |
| SCHEMBL1173871 | 0.72 | ATM (0.42) | ATMCYP3A4CYP2C19POLBOPRM1 | |
| SCHEMBL11620948 | 0.71 | CYP3A4 (0.37) | CYP3A4CYP2C19GAAALDH1A1LMNA | |
| SCHEMBL1868349 | 0.71 | ATM (0.41) | ATMPOLBOPRM1GAAALDH1A1 | |
| SCHEMBL9613980 | 0.70 | MEN1 (0.49) | CYP2C19OPRM1GAAALDH1A1BRD4 | |
| SCHEMBL9686765 | 0.69 | ATM (0.40) | ATMPOLBOPRM1GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5932747-A | Method for preparing 1,3-dioxane compounds | HUELS AKTIENGESELLSCHAFT (DE) | 1999-08-03 | — | — | US | disclosed |
| US-4521327-A | STRESS RESISTANCE, PHOTOSTABILITY, ELECTRICAL RESISTANCE, LOW BIREFRINGENCE | VEB WERK FUR FERNSEHELEKTRONIK IM VEB KOMBINAT MIKROELEKTRONIK (DD) | 1985-06-04 | — | — | US | disclosed |