Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 13/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 8/20 | 0.42 |
| ▸ | MBOAT4 | Q96T53 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9618180 | 0.94 | SRD5A1 (0.44) | SRD5A1SRD5A2MBOAT4 | |
| SCHEMBL8677535 | 0.86 | MBOAT4 (0.40) | SRD5A1SRD5A2MBOAT4 | |
| SCHEMBL9543229 | 0.84 | MBOAT4 (0.41) | SRD5A1SRD5A2MBOAT4 | |
| SCHEMBL9776615 | 0.83 | SRD5A1 (0.41) | SRD5A1SRD5A2MBOAT4 | |
| SCHEMBL7643438 | 0.81 | MBOAT4 (0.47) | SRD5A1SRD5A2MBOAT4 | |
| SCHEMBL10698417 | 0.79 | MBOAT4 (0.45) | SRD5A1SRD5A2MBOAT4 | |
| SCHEMBL9580259 | 0.77 | SRD5A1 (0.45) | SRD5A1SRD5A2MBOAT4 | |
| SCHEMBL5109022 | 0.75 | MBOAT4 (0.51) | SRD5A1SRD5A2MBOAT4 | |
| SCHEMBL5580932 | 0.75 | MBOAT4 (0.41) | SRD5A1SRD5A2MBOAT4 | |
| SCHEMBL9134492 | 0.74 | MBOAT4 (0.40) | SRD5A1SRD5A2MBOAT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992016233-A1 | PHARMACEUTICAL COMBINATION FOR THE TREATMENT OF PROSTATIC CANCER CONTAINING A 5 ALPHA REDUCTASE INHIBITOR AND AN ANTIANDROGEN | MERCK & CO., INC. (US) | 1992-10-01 | — | — | WO | disclosed |