Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.33 |
| ▸ | ATIC | P31939 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 3/20 | 0.32 |
| ▸ | PARP1 | P09874 | 5/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13735762 | 0.84 | ALDH1A1 (0.65) | ALDH1A1POLBRXFP1KDM4ECYP3A4 | |
| SCHEMBL13735766 | 0.81 | ALDH1A1 (0.63) | ALDH1A1POLBRXFP1KDM4ECYP3A4 | |
| SCHEMBL13736882 | 0.74 | ALDH1A1 (0.46) | ALDH1A1POLBRXFP1KDM4ECYP3A4 | |
| SCHEMBL414535 | 0.71 | ALDH1A1 (1.00) | ALDH1A1POLBRXFP1KDM4ECYP3A4 | |
| SCHEMBL5742205 | 0.67 | ALDH1A1 (0.52) | ALDH1A1POLBRXFP1KDM4ECYP3A4 | |
| SCHEMBL31608586 | 0.65 | ALDH1A1 (0.76) | ALDH1A1POLBRXFP1KDM4ECYP3A4 | |
| SCHEMBL2775270 | 0.64 | ALDH1A1 (0.44) | ALDH1A1POLBRXFP1KDM4ECYP3A4 | |
| SCHEMBL5165263 | 0.64 | ALDH1A1 (0.44) | ALDH1A1POLBRXFP1KDM4ECYP3A4 | |
| SCHEMBL10843943 | 0.64 | ALDH1A1 (0.44) | ALDH1A1POLBRXFP1 | |
| SCHEMBL10843945 | 0.63 | ALDH1A1 (0.42) | ALDH1A1POLBRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0515684-A1 | INHIBITOR OF DENATURED LDL FORMATION | Chugai Seiyaku Kabushiki Kaisha (JP) | 1992-12-02 | — | — | EP | disclosed |