Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | DHFR | P00374 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CASR | P41180 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CETP | P11597 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11544567 | 0.84 | TSHR (0.59) | TSHRDHFRMAPK1CNR2CNR1 | |
| SCHEMBL9708987 | 0.81 | POLB (0.51) | TSHRDHFRMAPK1L3MBTL1POLB | |
| SCHEMBL11684683 | 0.79 | TSHR (0.51) | TSHRMAPK1CNR2CNR1L3MBTL1 | |
| SCHEMBL22340711 | 0.79 | TSHR (0.70) | TSHRMAPK1CNR2CNR1ALDH1A1 | |
| SCHEMBL11131644 | 0.78 | TSHR (0.64) | TSHRMAPK1CNR2CNR1CETP | |
| SCHEMBL7324260 | 0.77 | TSHR (0.49) | TSHRMAPK1CNR2CNR1POLB | |
| SCHEMBL11469036 | 0.76 | TSHR (0.51) | TSHRMAPK1CNR2CNR1L3MBTL1 | |
| SCHEMBL22340783 | 0.76 | TSHR (0.70) | TSHRMAPK1CNR2CNR1ALDH1A1 | |
| SCHEMBL15720901 | 0.76 | KDM4E (0.73) | MAPK1L3MBTL1POLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL8351297 | 0.76 | DHFR (0.43) | DHFRSMN1; SMN2ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0515684-A1 | INHIBITOR OF DENATURED LDL FORMATION | Chugai Seiyaku Kabushiki Kaisha (JP) | 1992-12-02 | — | — | EP | disclosed |