Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | DHFR | P00374 | 2/20 | 0.48 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.45 |
| ▸ | TUBB | P07437 | 2/20 | 0.45 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.45 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.45 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.45 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.45 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.45 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.45 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.45 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7318334 | 0.86 | POLB (0.52) | POLBSMN1; SMN2MAPK1L3MBTL1KDM4E | |
| SCHEMBL15720901 | 0.81 | KDM4E (0.73) | POLBSMN1; SMN2MAPK1L3MBTL1KDM4E | |
| SCHEMBL9709038 | 0.81 | TSHR (0.59) | POLBSMN1; SMN2MAPK1L3MBTL1KDM4E | |
| SCHEMBL13177255 | 0.80 | KDM4E (0.47) | POLBSMN1; SMN2MAPK1KDM4EGAA | |
| SCHEMBL7268018 | 0.79 | KDM4E (0.65) | POLBSMN1; SMN2MAPK1L3MBTL1KDM4E | |
| SCHEMBL29066061 | 0.78 | TUBB1 (0.61) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL14266667 | 0.77 | TSHR (0.57) | MAPK1ALDH1A1TSHR | |
| SCHEMBL10889202 | 0.77 | CALM1 (0.56) | MAPK1TSHR | |
| SCHEMBL12933663 | 0.74 | PTGS2 (0.52) | MAPTALDH1A1DHFRTUBB4ATUBB | |
| SCHEMBL11680743 | 0.74 | TSHR (0.50) | POLBSMN1; SMN2MAPK1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0515684-A1 | INHIBITOR OF DENATURED LDL FORMATION | Chugai Seiyaku Kabushiki Kaisha (JP) | 1992-12-02 | — | — | EP | disclosed |