SCHEMBL9709232

SCHEMBL9709232

C[Si](C)(C)OC(=O)C(=CC(=O)O)C1CCCCC1

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9709351 0.80 ALDH1A1 (0.32) CES2CES1
SCHEMBL27619572 0.77 ALDH1A1 (0.44)
SCHEMBL1832495 0.76 EPHX1 (0.38) CES2CES1
SCHEMBL28436216 0.76 EPHX1 (0.38) CES2CES1
SCHEMBL27638615 0.75 ALDH1A1 (0.41)
SCHEMBL9709551 0.74
SCHEMBL1794603 0.74 CES2 (0.44) CES2CES1TSHR
SCHEMBL5086026 0.74 CES2 (0.44) CES2CES1TSHR
SCHEMBL164961 0.74 CES2 (0.44) CES2CES1TSHR
SCHEMBL164962 0.74 CES2 (0.44) CES2CES1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0244835-B1 LANGMUIR-BLODGETT ULTRATHIN MEMBRANE OF POLYFUMURATE NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1992-08-26 EP claimed
US-4907038-A Langmuir Blodgett ultrathin membrane of polyfumarate NIPPON OIL AND FATS CO., LTD. (JP) 1990-03-06 US claimed
EP-0244835-A2 Langmuir-Blodgett ultrathin membrane of polyfumurate NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1987-11-11 EP claimed
EP-0244835-B1 LANGMUIR-BLODGETT ULTRATHIN MEMBRANE OF POLYFUMURATE NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1992-08-26 EP disclosed
US-4907038-A Langmuir Blodgett ultrathin membrane of polyfumarate NIPPON OIL AND FATS CO., LTD. (JP) 1990-03-06 US disclosed