SCHEMBL9709505

SCHEMBL9709505

O=C1C=C(S(=O)(=O)Cl)c2ccccc2C1=O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 8/20 0.63
PTPRC P08575 5/20 0.50
MAPT P10636 2/20 0.50
KDM4E B2RXH2 1/20 0.50
ALDH1A1 P00352 1/20 0.50
CYP3A4 P08684 1/20 0.50
HPGD P15428 1/20 0.50
MAPK1 P28482 1/20 0.50
PTPN22 Q9Y2R2 1/20 0.50
NSD2 O96028 1/20 0.50
HKDC1 Q2TB90 1/20 0.50
CDC25B P30305 2/20 0.47
PTPRF P10586 1/20 0.47
MALT1 Q9UDY8 2/20 0.46
DNMT1 P26358 2/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
IDO1 P14902 1/20 0.43
DNMT3L Q9UJW3 1/20 0.43
DNMT3A Q9Y6K1 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9189540 0.83 CDC25B (0.50) PTPN1PTPRCMAPTKDM4EALDH1A1
SCHEMBL29397292 0.83 PTPN1 (0.63) PTPN1PTPRCMAPTKDM4EALDH1A1
SCHEMBL366178 0.83 PTPN1 (0.63) PTPN1PTPRCMAPTKDM4EALDH1A1
SCHEMBL423605 0.82 PTPN1 (0.61) PTPN1PTPRCMAPTKDM4EALDH1A1
Potassium SCHEMBL4798700 0.82 PTPN1 (0.61) PTPN1PTPRCMAPTKDM4EALDH1A1
Ammonia Solution, Strong SCHEMBL5163658 0.82 PTPN1 (0.61) PTPN1PTPRCMAPTKDM4EALDH1A1
SCHEMBL4181599 0.82 PTPN1 (0.61) PTPN1PTPRCMAPTKDM4EALDH1A1
SCHEMBL423604 0.82 PTPN1 (0.61) PTPN1PTPRCMAPTKDM4EALDH1A1
SCHEMBL20344209 0.80 SLC2A1 (0.43) PTPN1PTPRCMAPTKDM4EALDH1A1
Nitrogen SCHEMBL27516868 0.80 PTPN1 (0.59) PTPN1PTPRCMAPTKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0488712-A1 Positive photoresist composition HOECHST CELANESE CORPORATION (US) 1992-06-03 EP disclosed