Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 2/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29864731 | 0.84 | HDAC3 (0.37) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL9709476 | 0.83 | USP2 (0.31) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL16077490 | 0.78 | HDAC1 (0.40) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL9709605 | 0.77 | GRIK1 (0.41) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL10297782 | 0.72 | HDAC3 (0.38) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL12341109 | 0.72 | MEN1 (0.32) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL17344466 | 0.72 | TSHR (0.38) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL8723495 | 0.72 | HDAC3 (0.39) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL16326514 | 0.71 | HDAC6 (0.40) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL1101944 | 0.71 | LMNA (0.42) | HDAC3HDAC1HDAC2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0493324-A1 | Certain (arylsulfonamido- and pyridyl- or imidazolyl-)-substituted carboxylic acids and derivatives thereof | CIBA-GEIGY AG (CH) | 1992-07-01 | — | — | EP | disclosed |