Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 3/20 | 0.36 |
| ▸ | MGLL | Q99685 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.34 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL637189 | 0.88 | ALDH1A1 (0.53) | LMNAALDH1A1HDAC6HDAC3HDAC1 | |
| SCHEMBL14984822 | 0.86 | ALDH1A1 (0.61) | LMNAALDH1A1HDAC6HDAC3HDAC1 | |
| SCHEMBL30822463 | 0.84 | ALDH1A1 (0.65) | LMNAALDH1A1HDAC6HDAC3HDAC1 | |
| SCHEMBL31240249 | 0.84 | ALDH1A1 (0.65) | LMNAALDH1A1HDAC6HDAC3HDAC1 | |
| SCHEMBL12544697 | 0.84 | ALDH1A1 (0.65) | LMNAALDH1A1HDAC6HDAC3HDAC1 | |
| SCHEMBL8951105 | 0.84 | ALDH1A1 (0.65) | LMNAALDH1A1HDAC6HDAC3HDAC1 | |
| SCHEMBL12543741 | 0.84 | ALDH1A1 (0.65) | LMNAALDH1A1HDAC6HDAC3HDAC1 | |
| SCHEMBL21068995 | 0.83 | ALDH1A1 (0.37) | LMNAALDH1A1HDAC6HDAC3HDAC1 | |
| SCHEMBL6862125 | 0.80 | ALDH1A1 (0.39) | LMNAALDH1A1FAAHMGLLMAPT | |
| SCHEMBL4583910 | 0.80 | HDAC6 (0.42) | ALDH1A1HDAC6HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 196 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119630672-A | Camptothecin derivative and conjugate thereof, and preparation method and medical application thereof | 一线医药（杭州）有限公司 | 2025-03-14 | — | — | CN | disclosed |
| CN-118493978-B | Waterproof breathable polyester fiber fabric and production process thereof | 安徽金弘润新材料科技有限公司 | 2024-09-10 | — | — | CN | disclosed |
| CN-118493978-A | Waterproof breathable polyester fiber fabric and production process thereof | 安徽金弘润新材料科技有限公司 | 2024-08-16 | — | — | CN | disclosed |
| CN-107973809-B | Macrocyclic compounds as factor XIA inhibitors | 百时美施贵宝公司 | 2023-06-30 | — | — | CN | disclosed |
| CN-111378142-A | Force-induced response supramolecular polymer | 翁秋梅 | 2020-07-07 | — | — | CN | disclosed |
| US-20180177746-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ACUCELA INC. | 2018-06-28 | — | — | US | disclosed |
| EP-2627178-B1 | QUINAZOLINONE-TYPE COMPOUNDS AS CRTH2 ANTAGONISTS | MERCK SHARP & DOHME (US) | 2018-05-02 | — | — | EP | disclosed |
| US-9932309-B2 | 2-oxo-3,4-dihydropyridine-5-carboxylates and their use | UNIVERSITE DE LILLE 2 DROIT ET SANTE (FR) | 2018-04-03 | — | — | US | disclosed |
| US-9856265-B2 | Macrocyclic inhibitors of hepatitis C virus | JANSSEN SCIENCES IRELAND UC (IE) | 2018-01-02 | — | — | US | disclosed |
| CN-104995257-B | Hardening prevents powered organopolysiloxane composition and anti-band voltolisation silica epithelium | 信越聚合物株式会社 | 2017-11-24 | — | — | CN | disclosed |
| US-20050261325-A1 | Especially N-(3-carbonylamino3-substituted-propyl)spiro(indene- or indane-2,4'-piperidine derivatives, useful in treatment of inflammatory and immunoregulatory disorders, allergic diseases, atopic conditions, autoimmune disorders and atherosclerosis | MERCK SHARP & DOHME CORP. | 2005-11-24 | — | — | US | disclosed |
| EP-1558250-A1 | GAMMA-AMINOAMIDE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Merck & Co., Inc. (US) | 2005-08-03 | — | — | EP | disclosed |
| WO-2004041279-A1 | GAMMA-AMINOAMIDE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | MERCK & CO., INC. (US) | 2004-05-21 | — | — | WO | disclosed |
| EP-0548774-B1 | Process for producing a lactone or an ester | SUMITOMO CHEMICAL CO (JP) | 2000-03-15 | — | — | EP | disclosed |
| CN-1211232-A | Benzamidine derivatives substituted with amino acid and hydroxy acid derivatives and their use as anticoagulants | BERLEX LAB (US) | 1999-03-17 | — | — | CN | disclosed |
| US-5854410-A | Oligonucleoside cleavage compounds and therapies | GENTA INCORPORATED (US) | 1998-12-29 | — | — | US | disclosed |
| WO-1995026733-A1 | OLIGONUCLEOSIDE CLEAVAGE COMPOUNDS AND THERAPIES | GENTA INCORPORATED (US) | 1995-10-12 | — | — | WO | disclosed |
| US-5405974-A | Reacting a ketone, oxygen, an aromatic aldehyde using an aromatic solvent | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-04-11 | — | — | US | disclosed |
| EP-0548774-A1 | Process for producing a lactone or an ester | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-06-30 | — | — | EP | disclosed |
| EP-0425831-A2 | Contact lens | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1991-05-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261325-A1 | Especially N-(3-carbonylamino3-substituted-propyl)spiro(indene- or indane-2,4'-piperidine derivatives, useful in treatment of inflammatory and immunoregulatory disorders, allergic diseases, atopic conditions, autoimmune disorders and atherosclerosis | CCR1, CCR3, CCR2 | LMNA 3129/4885ALDH1A1 1345/4885HDAC6 1344/4885 |
| US-20180177746-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ALDH1A2, CLN6, AGER | LMNA 565/4885ALDH1A1 140/4885HDAC6 1207/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.