SCHEMBL9709571

SCHEMBL9709571

CCOC(=O)CCC(CCCc1cccnc1)OCCCNS(=O)(=O)c1ccc(Cl)cc1

nearest known ligand 0.67

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TBXAS1 P24557 20/20 0.67
TBXA2R P21731 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9709572 0.89 TBXAS1 (0.78) TBXAS1TBXA2R
SCHEMBL9709119 0.88 TBXAS1 (0.71) TBXAS1TBXA2R
SCHEMBL9710028 0.88 TBXAS1 (0.78) TBXAS1TBXA2R
SCHEMBL9733049 0.83 TBXAS1 (0.77) TBXAS1TBXA2R
SCHEMBL9732514 0.82 TBXAS1 (0.84) TBXAS1TBXA2R
SCHEMBL9732462 0.82 TBXAS1 (0.78) TBXAS1TBXA2R
SCHEMBL9732435 0.81 TBXAS1 (0.79) TBXAS1TBXA2R
SCHEMBL9732607 0.81 TBXAS1 (0.78) TBXAS1TBXA2R
SCHEMBL9709586 0.81 TBXAS1 (0.62) TBXAS1TBXA2R
SCHEMBL9709504 0.81 TBXAS1 (0.43) TBXAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0493324-A1 Certain (arylsulfonamido- and pyridyl- or imidazolyl-)-substituted carboxylic acids and derivatives thereof CIBA-GEIGY AG (CH) 1992-07-01 EP disclosed